AIM: To assess the treatment and tumor-related variables associated with outcome after treatment of spontaneously ruptured hepatocellular carcinoma (HCC). METHODS: Patients with ruptured HCC were identified. The complications, mortality and survival were assessed. The relationship between tumor size and the severity of hemoperitoneum and between tumor size and grade were examined. RESULTS: From January 1993 to January 2008, 556 patients with HCC with or without cirrhosis were evaluated; of which, 16 (2.87%) presented with spontaneous rupture. All but 1 patient had cirrhosis. Twelve patients underwent surgical resection while 4 underwent trans-cutaneous arterial catheter embolization (TAE) (trans-cutaneous arterial embolization). Early mortality (< 30 d) was 25% (4 of 16) and was inversely related to Child-Pugh score; 3 of the 4 early deaths occurred in patients treated with TAE with 1 of 12 occurring in the resected group. There was no correlation between tumor size and grade or between size and severity of hemoperitoneum. CONCLUSION: Tumor size did not correlate with severity of the hemoperitoneum. There was an inverse relationship between G1-G3 (grade of cellular differentiation) HCC and dimensions.
AIM: To assess the treatment and tumor-related variables associated with outcome after treatment of spontaneously ruptured hepatocellular carcinoma (HCC). METHODS:Patients with ruptured HCC were identified. The complications, mortality and survival were assessed. The relationship between tumor size and the severity of hemoperitoneum and between tumor size and grade were examined. RESULTS: From January 1993 to January 2008, 556 patients with HCC with or without cirrhosis were evaluated; of which, 16 (2.87%) presented with spontaneous rupture. All but 1 patient had cirrhosis. Twelve patients underwent surgical resection while 4 underwent trans-cutaneous arterial catheter embolization (TAE) (trans-cutaneous arterial embolization). Early mortality (< 30 d) was 25% (4 of 16) and was inversely related to Child-Pugh score; 3 of the 4 early deaths occurred in patients treated with TAE with 1 of 12 occurring in the resected group. There was no correlation between tumor size and grade or between size and severity of hemoperitoneum. CONCLUSION:Tumor size did not correlate with severity of the hemoperitoneum. There was an inverse relationship between G1-G3 (grade of cellular differentiation) HCC and dimensions.
Authors: A Tanaka; R Takeda; S Mukaihara; K Hayakawa; T Shibata; K Itoh; N Nishida; K Nakao; Y Fukuda; T Chiba; Y Yamaoka Journal: Int J Clin Oncol Date: 2001-12 Impact factor: 3.402
Authors: V Vergara; A Muratore; H Bouzari; R Polastri; A Ferrero; G Galatola; L Capussotti Journal: Eur J Surg Oncol Date: 2000-12 Impact factor: 4.424
Authors: Lilian Schwarz; Michael Bubenheim; Johanna Zemour; Astrid Herrero; Fabrice Muscari; Ahmet Ayav; Romain Riboud; Christian Ducerf; J-Marc Regimbeau; Hadrien Tranchart; Emilie Lermite; Gheorghe Petrovai; Amal Suhol; Alexandre Doussot; Lorenzo Capussotti; Jean Jacques Tuech; Yves Patrice Le Treut Journal: World J Surg Date: 2018-01 Impact factor: 3.352