Literature DB >> 20219388

Aortic root and cusp configuration determine aortic valve function.

Benjamin Oliver Bierbach1, Diana Aicher, Omar Abu Issa, Hagen Bomberg, Stefan Gräber, Petra Glombitza, Hans-Joachim Schäfers.   

Abstract

OBJECTIVE: Normalisation of aortic root and cusp configuration is a prerequisite for successful aortic valve repair (AVR). Using transthoracic echocardiography, we studied aortic root dimensions relative to body size in normal subjects and AVR patients.
METHODS: Aortic roots of healthy volunteers (n=130, age 27.9 ± 16.9 years) were examined for aortoventricular (AV), sinus (S), sinutubular-junction diameters (ST) and effective height (height difference between the AV plane and central coaptation point, eH) by transthoracic echocardiography. In 651 patients, after AVR residual aortic valve insufficiency (AI) and eH were determined. The relationships between eH versus root dimensions and eH versus residual AI were analysed by analysis of variance with Bonferroni post hoc testing.
RESULTS: Root dimensions correlated with each other and body size (r=0.74-0.91). In addition, a correlation between AV (r=0.73), sinus diameter (r=0.76), body height (r=0.77), body surface area (r=0.81) and eH was found. After AVR, eH was 9.8 ± 0.9 mm in 235 patients without postoperative AI, 9.4 ± 1.1mm in 370 with mild AI, 7.9 ± 1.4mm in 43 patients with moderate AI and 6 ± 1mm in three patients with severe AI. The difference in means of effective height between the groups was significant (p<0.005). Of 497 AVR patients with an eH ≥ 9 mm, 309 had no or trivial AI, 186 had mild AI and only two had moderate AI.
CONCLUSIONS: Parameters of aortic root dimensions follow a seemingly constant pattern in humans of different sizes. Effective height has a constant relationship to root dimensions and body size. In AVR, normalisation of eH leads to a high probability of normal or near-normal aortic valve function.
Copyright © 2010 European Association for Cardio-Thoracic Surgery. Published by Elsevier B.V. All rights reserved.

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Year:  2010        PMID: 20219388     DOI: 10.1016/j.ejcts.2010.01.060

Source DB:  PubMed          Journal:  Eur J Cardiothorac Surg        ISSN: 1010-7940            Impact factor:   4.191


  14 in total

1.  Complications after aortic valve repair and valve-sparing procedures.

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2.  Anatomy of the aortic root: implications for valve-sparing surgery.

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3.  Valve sparing root replacement: the remodeling technique with external ring annuloplasty.

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4.  Root remodeling for aortic root dilatation.

Authors:  Hans-Joachim Schäfers; Diana Aicher
Journal:  Ann Cardiothorac Surg       Date:  2013-01

Review 5.  Anatomy of the aortic root: implications for aortic root reconstruction.

Authors:  Takashi Kunihara
Journal:  Gen Thorac Cardiovasc Surg       Date:  2017-06-27

6.  Aortic annulus and the importance of annuloplasty.

Authors:  Pouya Youssefi; Emmanuel Lansac
Journal:  Indian J Thorac Cardiovasc Surg       Date:  2019-10-07

Review 7.  Geometry of cusp and root determines aortic valve function.

Authors:  Shunsuke Matsushima; Irem Karliova; Simon Gauer; Shunsuke Miyahara; Hans-Joachim Schäfers
Journal:  Indian J Thorac Cardiovasc Surg       Date:  2019-04-06

8.  Measurement of Aortic Valve Coaptation and Effective Height Using Echocardiography in Patients with Ventricular Septal Defects and Aortic Valve Prolapse.

Authors:  Satoru Iwashima; Hiroki Uchiyama; Takamichi Ishikawa; Kiyohiro Takigiku; Ken Takahashi; Manatomo Toyono; Nao Inoue; Masaki Nii
Journal:  Pediatr Cardiol       Date:  2017-01-21       Impact factor: 1.655

9.  Aortic valve adaptation to aortic root dilatation: insights into the mechanism of functional aortic regurgitation from 3-dimensional cardiac computed tomography.

Authors:  Dae-Hee Kim; Mark D Handschumacher; Robert A Levine; Byung Joo Sun; Jeong Yoon Jang; Dong Hyun Yang; Joon-Won Kang; Jong-Min Song; Duk-Hyun Kang; Tae-Hwan Lim; Jae-Kwan Song
Journal:  Circ Cardiovasc Imaging       Date:  2014-07-22       Impact factor: 7.792

10.  Aortitis as a Rare Cause of Aortic Aneurysm and Valve Regurgitation: Is Repair Precluded?

Authors:  Carlos Porras; Gemma Sanchez-Espin; Miguel Such; Jesús Sánchez-Ramos; Alicia Bautista-Pavés; Pilar Martín-de la Fuente; Josefa Ruiz; Norberto Ortego-Centeno; Isabel Rodríguez-Bailón; José María Melero
Journal:  Case Rep Cardiol       Date:  2018-02-13
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