Literature DB >> 20217244

Cushing's syndrome: why is diagnosis so difficult?

David C Aron1.   

Abstract

Practicing and perfecting the art of medicine demands recognition that uncertainty permeates all clinical decisions. When delivering clinical care, clinicians face a multiplicity of potential diagnoses, limitations in diagnostic capacity, and "sub-clinical" disease identified by tests rather than by clinical manifestations. In addition, clinicians must recognize the rapid changes in scientific knowledge needed to guide decisions. Cushing's syndrome is one of several disorders in which there may be considerable difficulty and delay in diagnosis. This article describes a current model of clinical reasoning, some of its challenges, and the application of the principles of clinical epidemiology to meet some of those challenges.

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Year:  2010        PMID： 20217244     DOI： 10.1007/s11154-010-9127-3

Source DB:  PubMed          Journal:  Rev Endocr Metab Disord        ISSN： 1389-9155            Impact factor:   6.514


  50 in total

1.  Diagnosis of Cushing's syndrome: A retrospective evaluation of clinical practice.

Authors:  Marie Muller; Tânia Longo Mazzuco; Monique Martinie; Ivan Bachelot; Olivier Chabre
Journal:  Eur J Intern Med       Date:  2006-08       Impact factor: 4.487

2.  Thinking about diagnostic thinking: a 30-year perspective.

Authors:  Arthur S Elstein
Journal:  Adv Health Sci Educ Theory Pract       Date:  2009-08-11       Impact factor: 3.853

3.  Cushing's syndrome--killing disease: discriminatory value of signs and symptoms aiding early diagnosis.

Authors:  E J Ross; D C Linch
Journal:  Lancet       Date:  1982-09-18       Impact factor: 79.321

4.  Clinical experience did not reduce the variance in physicians' estimates of pretest probability in a cross-sectional survey.

Authors:  Amos Cahan; Dan Gilon; Orly Manor; Ora Paltiel
Journal:  J Clin Epidemiol       Date:  2005-08-25       Impact factor: 6.437

Review 5.  Cushing's Syndrome: important issues in diagnosis and management.

Authors:  James W Findling; Hershel Raff
Journal:  J Clin Endocrinol Metab       Date:  2006-07-25       Impact factor: 5.958

Review 6.  Cyclic Cushing's syndrome: a clinical challenge.

Authors:  J R Meinardi; B H R Wolffenbuttel; R P F Dullaart
Journal:  Eur J Endocrinol       Date:  2007-09       Impact factor: 6.664

Review 7.  Dual-processing accounts of reasoning, judgment, and social cognition.

Authors:  Jonathan St B T Evans
Journal:  Annu Rev Psychol       Date:  2008       Impact factor: 24.137

8.  The prevalence and characteristic features of cyclicity and variability in Cushing's disease.

Authors:  Krystallenia I Alexandraki; Gregory A Kaltsas; Andrea M Isidori; Scott A Akker; William M Drake; Shern L Chew; John P Monson; G Michael Besser; Ashley B Grossman
Journal:  Eur J Endocrinol       Date:  2009-03-16       Impact factor: 6.664

9.  Development and validation of a 0.5 mg dexamethasone suppression test as an initial screening test for the diagnosis of ACTH-dependent Cushing's syndrome.

Authors:  Yutaka Oki; Kozo Hashimoto; Yukio Hirata; Yasumasa Iwasaki; Takeshi Nigawara; Masaru Doi; Satoru Sakihara; Kazunori Kageyama; Toshihiro Suda
Journal:  Endocr J       Date:  2009-08-25       Impact factor: 2.349

10.  Recommended evaluation of adrenal incidentalomas is costly, has high false-positive rates and confers a risk of fatal cancer that is similar to the risk of the adrenal lesion becoming malignant; time for a rethink?

Authors:  T J Cawood; P J Hunt; D O'Shea; D Cole; S Soule
Journal:  Eur J Endocrinol       Date:  2009-05-13       Impact factor: 6.664
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  6 in total

1.  Incremental healthcare resource utilization and costs in US patients with Cushing's disease compared with diabetes mellitus and population controls.

Authors:  Michael S Broder; Maureen P Neary; Eunice Chang; William H Ludlam
Journal:  Pituitary       Date:  2015-12       Impact factor: 4.107

Review 2.  Managing Cushing's disease: the state of the art.

Authors:  Annamaria Colao; Marco Boscaro; Diego Ferone; Felipe F Casanueva
Journal:  Endocrine       Date:  2014-01-11       Impact factor: 3.633

3.  CUSHING'S SYNDROME CAUSED BY AN ADRENOCORTICAL CARCINOMA AFTER A BARIATRIC SURGERY: CASE REPORT.

Authors:  Kátia Elisabete Pires Souto; Daniela Aline Pereira; Mauricio Jacques Ramos; Alberto Salgueiro Molinari; Daniel de Carvalho Damin
Journal:  Arq Bras Cir Dig       Date:  2015

4.  A long diagnostic delay in patients with Hereditary Haemorrhagic Telangiectasia: a questionnaire-based retrospective study.

Authors:  Paola Pierucci; Gennaro M Lenato; Patrizia Suppressa; Patrizia Lastella; Vincenzo Triggiani; Raffaella Valerio; Mario Comelli; Daniela Salvante; Alessandro Stella; Nicoletta Resta; Giancarlo Logroscino; Francesco Resta; Carlo Sabbà
Journal:  Orphanet J Rare Dis       Date:  2012-06-07       Impact factor: 4.123

5.  Cushing's syndrome: Stepwise approach to diagnosis.

Authors:  Anurag R Lila; Vijaya Sarathi; Varsha S Jagtap; Tushar Bandgar; Padmavathy Menon; Nalini S Shah
Journal:  Indian J Endocrinol Metab       Date:  2011-10

6.  Demographic Characteristics, Etiology, and Comorbidities of Patients with Cushing's Syndrome: A 10-Year Retrospective Study at a Large General Hospital in China.

Authors:  Jingya Zhou; Meng Zhang; Xue Bai; Shengnan Cui; Cheng Pang; Lin Lu; Haiyu Pang; Xiaopeng Guo; Yi Wang; Bing Xing
Journal:  Int J Endocrinol       Date:  2019-02-19       Impact factor: 3.257
  6 in total

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