Literature DB >> 20216957

Rapid detection of natriuretic peptides by a microfluidic LabChip analyzer with DNA aptamers: Application of natriuretic peptide detection.

Ming-Cheng Lin, Jiraporn Nawarak, Tai-Yuan Chen, Hsien-Yu Tsai, Jung-Feng Hsieh, Supachok Sinchaikul, Shui-Tein Chen.   

Abstract

Rapid detection of brain natriuretic peptide (BNP) concentration can be used for the diagnosis of acute heart failure and for the evaluation of the effectiveness of a clinical therapy. We used the systematic evolution of ligands by exponential enrichment method to develop DNA aptamers for BNP whose sequences were determined by cloning method and consensus sequence analysis. A total of eight conserved sequences was identified. By combining the fluorescent-labeled aptamers with fast protein lab-on-chip analysis, we could achieve quantification of BNP concentrations with high speed, sensitivity, and specificity.

Entities:  

Year:  2009        PMID： 20216957      PMCID： PMC2835275          DOI： 10.1063/1.3194283

Source DB:  PubMed          Journal:  Biomicrofluidics        ISSN： 1932-1058            Impact factor:   2.800


  36 in total

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Journal:  Nature       Date:  1992-02-06       Impact factor: 49.962

5.  The neighbor-joining method: a new method for reconstructing phylogenetic trees.

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Journal:  Mol Biol Evol       Date:  1987-07       Impact factor: 16.240

6.  Cardiac-specific attenuation of natriuretic peptide A receptor activity accentuates adverse cardiac remodeling and mortality in response to pressure overload.

Authors:  Jeetendra B Patel; Maria L Valencik; Allison M Pritchett; John C Burnett; John A McDonald; Margaret M Redfield
Journal:  Am J Physiol Heart Circ Physiol       Date:  2005-03-18       Impact factor: 4.733

7.  The use of aptamers in large arrays for molecular diagnostics.

Authors:  E N Brody; M C Willis; J D Smith; S Jayasena; D Zichi; L Gold
Journal:  Mol Diagn       Date:  1999-12

8.  Comparative studies on the analysis of glycoproteins and lipopolysaccharides by the gel-based microchip and SDS-PAGE.

Authors:  Jung-Feng Hsieh; Shui-Tein Chen
Journal:  Biomicrofluidics       Date:  2007-01-01       Impact factor: 2.800

9.  Relationship between Cardiofemoral Index and the plasma concentration of brain natriuretic peptide in anemic fetuses associated with Rh alloimmunization.

Authors:  Ana Luíza Penido Ferreira; Zilma Silveira Nogueira Reis; Jacqueline Braga; Henrique Vitor Leite; Antônio Carlos Vieira Cabral
Journal:  Arch Gynecol Obstet       Date:  2008-07-16       Impact factor: 2.344

10.  In vitro selection of RNA aptamers specific for cyanocobalamin.

Authors:  J R Lorsch; J W Szostak
Journal:  Biochemistry       Date:  1994-02-01       Impact factor: 3.162
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  3 in total

1.  Preliminary Development of a DNA Aptamer-Magnetic Bead Capture Electrochemiluminescence Sandwich Assay for Brain Natriuretic Peptide.

Authors:  John G Bruno; Alicia M Richarte; Taylor Phillips
Journal:  Microchem J       Date:  2014-07-01       Impact factor: 4.821

Review 2.  Aptamers Targeting Cardiac Biomarkers as an Analytical Tool for the Diagnostics of Cardiovascular Diseases: A Review.

Authors:  Natalia Komarova; Olga Panova; Alexey Titov; Alexander Kuznetsov
Journal:  Biomedicines       Date:  2022-05-06

Review 3.  Screening of aptamers on microfluidic systems for clinical applications.

Authors:  Chen-Hsun Weng; Chao-Jyun Huang; Gwo-Bin Lee
Journal:  Sensors (Basel)       Date:  2012-07-11       Impact factor: 3.576
  3 in total

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