Literature DB >> 20216432

Probiotics as therapy in gastroenterology: a study of physician opinions and recommendations.

Michael D Williams1, Christina Y Ha, Matthew A Ciorba.   

Abstract

GOALS: The objective of this study was to determine how gastroenterologists perceive and use probiotic-based therapies in practice.
BACKGROUND: In the United States, there has been a recent increase in research investigating the therapeutic capacities of probiotics in human disease and an accompanying increase in product availability and marketing. How medical care providers have interpreted the available literature and incorporated it into their practice has not been earlier assessed. STUDY: A 16-question survey (see Survey, Supplemental Digital Content 1, http://links.lww.com/JCG/A14) was distributed to practicing gastroenterologists and physicians with a specific interest in GI disorders within a large metropolitan area.
RESULTS: All physicians responded that they believed probiotics to be safe for most patients and 98% responded that probiotics have a role in treating gastrointestinal illnesses or symptoms. Currently 93% of physicians have patients taking probiotics most often for irritable bowel syndrome. Commonly used probiotics included yogurt-based products, Bifidobacterium infantis 35624 (Align), and VSL#3. Most surveyed physicians recommended probiotics for irritable bowel syndrome, antibiotic, and Clostridium difficile-associated diarrhea because they believed that the literature supports their usage for these conditions. However, physician practice patterns did not consistently correlate with published, expert-panel-generated recommendations for evidence-based probiotic use.
CONCLUSIONS: This study suggests most gastrointestinal disease specialists recognize a role for and have used probiotics as part of their therapeutic armamentarium; however, the effective implementation of this practice will benefit from additional supporting studies and the eventual development of clinical practice guidelines supported by the major gastroenterology societies.

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Mesh:

Year:  2010        PMID: 20216432      PMCID: PMC4094138          DOI: 10.1097/MCG.0b013e3181d47f5b

Source DB:  PubMed          Journal:  J Clin Gastroenterol        ISSN: 0192-0790            Impact factor:   3.062


  20 in total

Review 1.  Recommendations for probiotic use.

Authors:  Martin H Floch; Karen K Madsen; David J A Jenkins; Stefano Guandalini; Jeffery A Katz; Andrew Onderdonk; W Allan Walker; Richard N Fedorak; Michael Camilleri
Journal:  J Clin Gastroenterol       Date:  2006-03       Impact factor: 3.062

Review 2.  Use of probiotics in humans: an analysis of the literature.

Authors:  Martin H Floch; David C Montrose
Journal:  Gastroenterol Clin North Am       Date:  2005-09       Impact factor: 3.806

3.  Saccharomyces cerevisiae fungemia after Saccharomyces boulardii treatment in immunocompromised patients.

Authors:  Arnoldo J Riquelme; Mario A Calvo; Ana M Guzmán; María S Depix; Patricia García; Carlos Pérez; Marco Arrese; Jaime A Labarca
Journal:  J Clin Gastroenterol       Date:  2003-01       Impact factor: 3.062

4.  Liver transplantation for hepatocellular carcinoma: a survey of practices.

Authors:  Erik J Van Kleek; Jonathan M Schwartz; Stephen C Rayhill; Hugo R Rosen; Scott J Cotler
Journal:  J Clin Gastroenterol       Date:  2006-08       Impact factor: 3.062

5.  A randomized controlled trial of a probiotic combination VSL# 3 and placebo in irritable bowel syndrome with bloating.

Authors:  H J Kim; M I Vazquez Roque; M Camilleri; D Stephens; D D Burton; K Baxter; G Thomforde; A R Zinsmeister
Journal:  Neurogastroenterol Motil       Date:  2005-10       Impact factor: 3.598

6.  Lactobacillus and bifidobacterium in irritable bowel syndrome: symptom responses and relationship to cytokine profiles.

Authors:  Liam O'Mahony; Jane McCarthy; Peter Kelly; George Hurley; Fangyi Luo; Kersang Chen; Gerald C O'Sullivan; Barry Kiely; J Kevin Collins; Fergus Shanahan; Eamonn M M Quigley
Journal:  Gastroenterology       Date:  2005-03       Impact factor: 22.682

7.  Effect of Lactobacillus plantarum 299v on colonic fermentation and symptoms of irritable bowel syndrome.

Authors:  S Sen; M M Mullan; T J Parker; J T Woolner; S A Tarry; J O Hunter
Journal:  Dig Dis Sci       Date:  2002-11       Impact factor: 3.199

8.  Efficacy of an encapsulated probiotic Bifidobacterium infantis 35624 in women with irritable bowel syndrome.

Authors:  Peter J Whorwell; Linda Altringer; Jorge Morel; Yvonne Bond; Duane Charbonneau; Liam O'Mahony; Barry Kiely; Fergus Shanahan; Eamonn M M Quigley
Journal:  Am J Gastroenterol       Date:  2006-07       Impact factor: 10.864

9.  The probiotic preparation, VSL#3 induces remission in patients with mild-to-moderately active ulcerative colitis.

Authors:  Ajit Sood; Vandana Midha; Govind K Makharia; Vineet Ahuja; Dinesh Singal; Pooja Goswami; Rakesh K Tandon
Journal:  Clin Gastroenterol Hepatol       Date:  2009-07-22       Impact factor: 11.382

Review 10.  Therapeutic manipulation of the enteric microflora in inflammatory bowel diseases: antibiotics, probiotics, and prebiotics.

Authors:  R Balfour Sartor
Journal:  Gastroenterology       Date:  2004-05       Impact factor: 22.682

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  16 in total

Review 1.  A gastroenterologist's guide to probiotics.

Authors:  Matthew A Ciorba
Journal:  Clin Gastroenterol Hepatol       Date:  2012-04-10       Impact factor: 11.382

2.  Advances in understanding and improving gastrointestinal symptoms during supportive and palliative care: a decade of progress.

Authors:  Matthew A Ciorba
Journal:  Curr Opin Support Palliat Care       Date:  2016-06       Impact factor: 2.302

3.  How patients view probiotics: findings from a multicenter study of patients with inflammatory bowel disease and irritable bowel syndrome.

Authors:  MaryBeth Mercer; Margaret A Brinich; Gail Geller; Krista Harrison; Janelle Highland; Katherine James; Patricia Marshall; Jennifer B McCormick; Jon Tilburt; Jean-Paul Achkar; Ruth M Farrell; Richard R Sharp
Journal:  J Clin Gastroenterol       Date:  2012-02       Impact factor: 3.062

4.  PURLs: prescribing an antibiotic? Pair it with probiotics.

Authors:  Blake Rodgers; Kate Kirley; Anne Mounsey
Journal:  J Fam Pract       Date:  2013-03       Impact factor: 0.493

5.  AGA Technical Review on the Role of Probiotics in the Management of Gastrointestinal Disorders.

Authors:  Geoffrey A Preidis; Adam V Weizman; Purna C Kashyap; Rebecca L Morgan
Journal:  Gastroenterology       Date:  2020-06-09       Impact factor: 22.682

6.  Dose-response effect of Bifidobacterium lactis HN019 on whole gut transit time and functional gastrointestinal symptoms in adults.

Authors:  Philip A Waller; Pramod K Gopal; Gregory J Leyer; Arthur C Ouwehand; Cheryl Reifer; Morgan E Stewart; Larry E Miller
Journal:  Scand J Gastroenterol       Date:  2011-06-13       Impact factor: 2.423

7.  Lactobacillus probiotic protects intestinal epithelium from radiation injury in a TLR-2/cyclo-oxygenase-2-dependent manner.

Authors:  Matthew A Ciorba; Terrence E Riehl; M Suprada Rao; Clara Moon; Xueping Ee; Gerardo M Nava; Monica R Walker; Jeffrey M Marinshaw; Thaddeus S Stappenbeck; William F Stenson
Journal:  Gut       Date:  2011-10-24       Impact factor: 23.059

Review 8.  Chronic Critical Illness and PICS Nutritional Strategies.

Authors:  Martin D Rosenthal; Erin L Vanzant; Frederick A Moore
Journal:  J Clin Med       Date:  2021-05-25       Impact factor: 4.241

9.  Phylogenetic identification of bacterial MazF toxin protein motifs among probiotic strains and foodborne pathogens and potential implications of engineered probiotic intervention in food.

Authors:  Xianghe Yan; Joshua B Gurtler; Pina M Fratamico; Jing Hu; Vijay K Juneja
Journal:  Cell Biosci       Date:  2012-11-27       Impact factor: 7.133

Review 10.  Systematic review: probiotics in the management of lower gastrointestinal symptoms in clinical practice -- an evidence-based international guide.

Authors:  A P S Hungin; C Mulligan; B Pot; P Whorwell; L Agréus; P Fracasso; C Lionis; J Mendive; J-M Philippart de Foy; G Rubin; C Winchester; N de Wit
Journal:  Aliment Pharmacol Ther       Date:  2013-08-27       Impact factor: 8.171

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