Literature DB >> 20215812

Does the histamine H4 receptor have a pro- or anti-inflammatory role in murine bronchial asthma?

Detlef Neumann1, Silke Beermann, Roland Seifert.   

Abstract

The histamine H4 receptor is expressed preferentially on immune cells, indicating a possible role of the H4 receptor in inflammation. Studies of inflammation in several animal models point to a pro-inflammatory function of the H4 receptor. However, studies on experimental murine bronchial asthma yielded conflicting results, a fact which is neglected in most H4 receptor publications. Therefore, the present review critically analyzes available data on the role of the H4 receptor in the murine bronchial asthma model. 2010 S. Karger AG, Basel.

Entities:  

Mesh：

Substances：

Year:  2010        PMID： 20215812     DOI： 10.1159/000285088

Source DB:  PubMed          Journal:  Pharmacology        ISSN： 0031-7012            Impact factor:   2.547


  10 in total

Review 1.  The role of the histamine H4 receptor in atopic dermatitis.

Authors:  Susanne Mommert; Maria Gschwandtner; Ralf Gutzmer; Thomas Werfel
Journal:  Curr Allergy Asthma Rep       Date:  2011-02       Impact factor: 4.806

2.  Nothing to sneeze at.

Authors:  Erica Westly
Journal:  Nat Med       Date:  2010-10       Impact factor: 53.440

3.  Expression and functional properties of canine, rat, and murine histamine H₄ receptors in Sf9 insect cells.

Authors:  David Schnell; Irena Brunskole; Katerina Ladova; Erich H Schneider; Patrick Igel; Stefan Dove; Armin Buschauer; Roland Seifert
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2011-02-27       Impact factor: 3.000

4.  The dual H3/4R antagonist thioperamide does not fully mimic the effects of the 'standard' H4R antagonist JNJ 7777120 in experimental murine asthma.

Authors:  Detlef Neumann; Silke Beermann; Heike Burhenne; Silke Glage; Christina Hartwig; Roland Seifert
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2013-07-03       Impact factor: 3.000

Review 5.  Key mediators in the immunopathogenesis of allergic asthma.

Authors:  Sannette Hall; Devendra K Agrawal
Journal:  Int Immunopharmacol       Date:  2014-06-13       Impact factor: 4.932

6.  Differential effects of functionally different histamine H4 receptor ligands on acute irritant dermatitis in mice.

Authors:  Maristella Adami; Cristina Micheloni; Daniela Grandi; Holger Stark
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2018-08-25       Impact factor: 3.000

7.  Thioperamide induces CD4 CD25 Foxp3 regulatory T lymphocytes in the lung mucosa of allergic mice through its action on dendritic cells.

Authors:  Maria Marta Amaral; Carolina A Alvarez; Cecilia Langellotti; Carolina Jancic; Gabriela Salamone; Jorge Geffner; Mónica Vermeulen
Journal:  J Asthma Allergy       Date:  2011-09-26

8.  Opposite effects of mepyramine on JNJ 7777120-induced amelioration of experimentally induced asthma in mice in sensitization and provocation.

Authors:  Silke Beermann; Silke Glage; Danny Jonigk; Roland Seifert; Detlef Neumann
Journal:  PLoS One       Date:  2012-01-17       Impact factor: 3.240

9.  Luciferase reporter gene assay on human, murine and rat histamine H4 receptor orthologs: correlations and discrepancies between distal and proximal readouts.

Authors:  Uwe Nordemann; David Wifling; David Schnell; Günther Bernhardt; Holger Stark; Roland Seifert; Armin Buschauer
Journal:  PLoS One       Date:  2013-09-02       Impact factor: 3.240

10.  Distinct signalling pathways of murine histamine H1- and H4-receptors expressed at comparable levels in HEK293 cells.

Authors:  Silke Beermann; Marcus Vauth; Rabea Hein; Roland Seifert; Detlef Neumann
Journal:  PLoS One       Date:  2014-09-22       Impact factor: 3.240
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.