Nelson Z Galante1, Gustavo A Dib, José O Medina-Pestana. 1. Hospital do Rim e Hipertensão, Department of Medicine, Division of Nephrology, Federal University of São Paulo, Rua Borges Lagoa 960, Villa Clementino, São Paulo - SP, Brazil.
Abstract
BACKGROUND: Intellectual disability (ID) in patients with chronic kidney disease is a relative contraindication for kidney transplantation. METHODS: We analysed a retrospective cohort of 16 recipients of kidney transplantation with ID and 83 controls. RESULTS: Graft survival at 5 years was similar between patients (81.2%) and controls (80.2%), P = 0.9. Patient survival at 5 years was lower among patients (81.2% versus 94.4%, P < 0.05). Patients had more infection episodes, but no risk factors were identified. CONCLUSION: Although recipients with ID have lower long-term patient survival, the equivalent graft survival rates support the indication of renal transplantation in such disability.
BACKGROUND: Intellectual disability (ID) in patients with chronic kidney disease is a relative contraindication for kidney transplantation. METHODS: We analysed a retrospective cohort of 16 recipients of kidney transplantation with ID and 83 controls. RESULTS: Graft survival at 5 years was similar between patients (81.2%) and controls (80.2%), P = 0.9. Patient survival at 5 years was lower among patients (81.2% versus 94.4%, P < 0.05). Patients had more infection episodes, but no risk factors were identified. CONCLUSION: Although recipients with ID have lower long-term patient survival, the equivalent graft survival rates support the indication of renal transplantation in such disability.
Authors: Aaron Wightman; Bessie Young; Miranda Bradford; André Dick; Patrick Healey; Ruth McDonald; Jodi Smith Journal: Pediatr Transplant Date: 2014-08-19
Authors: Emily M Rosenberger; Kristen R Fox; Andrea F DiMartini; Mary Amanda Dew Journal: Curr Opin Organ Transplant Date: 2012-10 Impact factor: 2.640