Literature DB >> 20214473

The 10 x '20 Initiative: pursuing a global commitment to develop 10 new antibacterial drugs by 2020.

.   

Abstract

The time has come for a global commitment to develop new antibacterial drugs. Current data document the impending disaster due to the confluence of decreasing investment in antibacterial drug research and development concomitant with the documented rapid increase in the level of resistance to currently licensed drugs. Despite the good faith efforts of many individuals, professional societies, and governmental agencies, the looming crisis has only worsened over the past decade.

Mesh：

Substances：

Year:  2010        PMID： 20214473     DOI： 10.1086/652237

Source DB:  PubMed          Journal:  Clin Infect Dis        ISSN： 1058-4838            Impact factor:   9.079


  152 in total

1.  Antibacterial R&D incentives.

Authors:  Ramanan Laxminarayan; John H Powers
Journal:  Nat Rev Drug Discov       Date:  2011-09-30       Impact factor: 84.694

2.  Predicting the in vivo mechanism of action for drug leads using NMR metabolomics.

Authors:  Steven Halouska; Robert J Fenton; Raúl G Barletta; Robert Powers
Journal:  ACS Chem Biol       Date:  2011-12-01       Impact factor: 5.100

3.  Variants of β-lactamase KPC-2 that are resistant to inhibition by avibactam.

Authors:  Krisztina M Papp-Wallace; Marisa L Winkler; Magdalena A Taracila; Robert A Bonomo
Journal:  Antimicrob Agents Chemother       Date:  2015-02-09       Impact factor: 5.191

Review 4.  Development of novel antibacterial drugs to combat multiple resistant organisms.

Authors:  Matteo Bassetti; Elda Righi
Journal:  Langenbecks Arch Surg       Date:  2015-02-11       Impact factor: 3.445

5.  In vivo efficacy of the novel aminoglycoside ACHN-490 in murine infection models.

Authors:  Noe Reyes; James B Aggen; Corwin F Kostrub
Journal:  Antimicrob Agents Chemother       Date:  2011-01-31       Impact factor: 5.191

6.  Pharmacokinetics of four different brands of colistimethate and formed colistin in rats.

Authors:  Hui He; Ji-Chang Li; Roger L Nation; Jovan Jacob; Gong Chen; Hee Ji Lee; Brian T Tsuji; Philip E Thompson; Kade Roberts; Tony Velkov; Jian Li
Journal:  J Antimicrob Chemother       Date:  2013-06-07       Impact factor: 5.790

7.  Small molecule inhibitors of trans-translation have broad-spectrum antibiotic activity.

Authors:  Nitya S Ramadoss; John N Alumasa; Lin Cheng; Yu Wang; Sharon Li; Benjamin S Chambers; Hoon Chang; Arnab K Chatterjee; Achim Brinker; Ingo H Engels; Kenneth C Keiler
Journal:  Proc Natl Acad Sci U S A       Date:  2013-06-03       Impact factor: 11.205

8.  Occurrence of an environmental Acinetobacter baumannii strain similar to a clinical isolate in paleosol from Croatia.

Authors:  Jasna Hrenovic; Goran Durn; Ivana Goic-Barisic; Ana Kovacic
Journal:  Appl Environ Microbiol       Date:  2014-02-28       Impact factor: 4.792

9.  Large retrospective evaluation of the effectiveness and safety of ceftaroline fosamil therapy.

Authors:  Anthony M Casapao; Susan L Davis; Viktorija O Barr; Kenneth P Klinker; Debra A Goff; Katie E Barber; Keith S Kaye; Ryan P Mynatt; Leah M Molloy; Jason M Pogue; Michael J Rybak
Journal:  Antimicrob Agents Chemother       Date:  2014-02-18       Impact factor: 5.191

10.  Applicability of Outpatient Quality Indicators for Appropriate Antibiotic Use in a Primary Health Care Area: a Point Prevalence Survey.

Authors:  Pablo March-López; Rosa Madridejos; Rosa Tomas; Lucía Boix-Palop; Paula Arcenillas; Lucía Gómez; Emma Padilla; Mariona Xercavins; Laura Martinez; Úrsula Massats; Cristina Badia; Joan Manuel Sánchez Lledó; Alberto Domingo Casino; Jordi Nicolás; Esther Calbo
Journal:  Antimicrob Agents Chemother       Date:  2020-10-20       Impact factor: 5.191
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.