Literature DB >> 20214198

Cool-tip 10-mm electrode useful for radiofrequency ablation of hepatocellular carcinoma.

Noritaka Wakui1, Kazunari Iida, Ryuji Takayama, Kazue Shiozawa, Masayoshi Takahashi, Takashi Ikehara, Hidenari Nagai, Manabu Watanabe, Koji Ishii, Yasukiyo Sumino.   

Abstract

BACKGROUND/AIMS: Whether a cool-tip 10mm electrode is useful for radiofrequency ablation (RFA) of hepatocellular carcinoma (HCC) has not been established. Accordingly, the present study goal was to determine this electrode is indicated for RFA of HCC.
METHODOLOGY: This study was conducted with 30 HCC patients who were treated with a cool-tip 10-mm electrode over a period of about 3 years. Ten had hypervascular HCC nodules and 20 had hypovascular HCC nodules; mean tumor diameter was 10.5 +/- 1.8mm. Patients underwent follow-up CT scans every 3 to 6 months to detect local progression.
RESULTS: Of the 30 lesions, 4 (13.3%) showed local progression. Enhanced CT imaging of the four cases with local progression revealed that two had hypervascular HCC. The remaining two cases had hypovascular HCC.
CONCLUSIONS: The present study results suggest that, RFA with a cool-tip 10-mm electrode is indicated in cases of hypovascular HCC nodules if the lesion diameter is no more than 10mm. In addition, in order to avoid skin burns, only lesions at a depth of at least 16mm below the liver surface are suitable for this treatment. Because of its lesser invasiveness, the cool-tip 10-mm electrode appears to be more useful than other, more powerful, devices in patients with hepatic carcinoma.

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Year:  2009        PMID: 20214198

Source DB:  PubMed          Journal:  Hepatogastroenterology        ISSN: 0172-6390


  2 in total

1.  Radiofrequency ablation of liver tumors: Actual limitations and potential solutions in the future.

Authors:  Beat M Künzli; Paolo Abitabile; Christoph A Maurer
Journal:  World J Hepatol       Date:  2011-01-27

2.  Use of radiofrequency ablation in the treatment of hepatocellular carcinoma: Experience of ablation protocols.

Authors:  Takahashi Masayoshi; Noritaka Wakui; Yasukiyo Sumino
Journal:  Exp Ther Med       Date:  2012-09-13       Impact factor: 2.447

  2 in total

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