Literature DB >> 20213296

Can the caudal extent of fusion in the surgical treatment of scoliosis in Duchenne muscular dystrophy be stopped at lumbar 5?

Masashi Takaso1, Toshiyuki Nakazawa, Takayuki Imura, Masaki Ueno, Wataru Saito, Ryousuke Shintani, Kazuhisa Takahashi, Masashi Yamazaki, Seiji Ohtori, Makihito Okamoto, Takashi Masaki, Hirotsugu Okamoto, Toshiyuki Okutomi, Kazuhiro Ishii, Yasuhiro Ueda.   

Abstract

Instrumentation and fusion to the sacrum/pelvis has been a mainstay in the surgical treatment of scoliosis in Duchenne muscular dystrophy (DMD) and is recommended to correct pelvic obliquity. The caudal extent of instrumentation and fusion in the surgical treatment of scoliosis in DMD has remained a matter of considerable debate, and there have been few studies on the use of segmental pedicle screw instrumentation for this pathology. From 2004 to 2007, a total of 28 patients with DMD underwent segmental pedicle screw instrumentation and fusion only to L5. Assessment was performed clinically and with radiologic measurements. All patients had a curve with the apex at L2 or higher preoperatively. Preoperative coronal curve averaged 74 degrees, with a postoperative mean of 14 degrees, and 17 degrees at the last follow-up. The pelvic obliquity improved from 17 degrees preoperatively to 6 degrees postoperatively, and 6 degrees at the last follow-up. Good sagittal plane alignment was recreated after surgery and maintained long term. In 23 patients with a preoperative L5 tilt of less than 15 degrees, the pelvic obliquity was effectively corrected to less than 10 degrees and maintained by adequately addressing spinal deformity, while five patients with a preoperative L5 tilt of more than 15 degrees had a postoperative pelvic obliquity of more than 15 degrees. Segmental pedicle screw instrumentation and fusion to L5 was effective and safe in patients with DMD scoliosis with a minimal L5 tilt (<15 degrees) and a curve with the apex at L2 or higher, both initially and long term, obviating the need for fixation to the sacrum/pelvis. Segmental pedicle screw instrumentation and fusion to L5 was safe and effective in patients with DMD scoliosis with stable L5/S1 articulation as evidenced by a minimal L5 tilt of less than 15 degrees, even though pelvic obliquity was significant. There was no major complication. With rigid segmental pedicle screw instrumentation, the caudal extent of fusion in the treatment of DMD scoliosis should be determined by the degree of L5 tilt. This method in appropriate patients can be a viable alternative to instrumentation and fusion to the sacrum/pelvis in the surgical treatment of DMD scoliosis.

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Year:  2010        PMID: 20213296      PMCID: PMC2899950          DOI: 10.1007/s00586-010-1347-4

Source DB:  PubMed          Journal:  Eur Spine J        ISSN: 0940-6719            Impact factor:   3.134


  39 in total

1.  Spinal fusion in patients with Duchenne's muscular dystrophy and a low forced vital capacity.

Authors:  A Marsh; G Edge; J Lehovsky
Journal:  Eur Spine J       Date:  2003-05-14       Impact factor: 3.134

2.  Spinal stabilisation in Duchenne muscular dystrophy.

Authors:  C S Galasko; C Delaney; P Morris
Journal:  J Bone Joint Surg Br       Date:  1992-03

3.  Iliosacral screw fixation for pelvic obliquity in neuromuscular scoliosis. A long-term follow-up study.

Authors:  L T Miladi; I B Ghanem; M M Draoui; R D Zeller; J F Dubousset
Journal:  Spine (Phila Pa 1976)       Date:  1997-08-01       Impact factor: 3.468

4.  Predominantly posterior instrumentation and fusion in neuromuscular and neurogenic scoliosis in children and adolescents.

Authors:  U Stricker; H Moser; M Aebi
Journal:  Eur Spine J       Date:  1996       Impact factor: 3.134

5.  The treatment of scoliosis in muscular dystrophy using modified Luque and Harrington-Luque instrumentation.

Authors:  G Bentley; F Haddad; T M Bull; D Seingry
Journal:  J Bone Joint Surg Br       Date:  2001-01

6.  The Galveston technique for L rod instrumentation of the scoliotic spine.

Authors:  B L Allen; R L Ferguson
Journal:  Spine (Phila Pa 1976)       Date:  1982 May-Jun       Impact factor: 3.468

7.  The outcome of scoliosis surgery in the severely physically handicapped child. An objective and subjective assessment.

Authors:  G N Askin; R Hallett; N Hare; J K Webb
Journal:  Spine (Phila Pa 1976)       Date:  1997-01-01       Impact factor: 3.468

8.  Progression of scoliosis in Duchenne muscular dystrophy.

Authors:  A D Smith; J Koreska; C F Moseley
Journal:  J Bone Joint Surg Am       Date:  1989-08       Impact factor: 5.284

9.  Spinal fusion in Duchenne muscular dystrophy--fixation and fusion to the sacropelvis?

Authors:  S J Mubarak; W D Morin; J Leach
Journal:  J Pediatr Orthop       Date:  1993 Nov-Dec       Impact factor: 2.324

10.  Treatment of neuromuscular scoliosis with posterior-only pedicle screw fixation.

Authors:  Hitesh N Modi; Seung-Woo Suh; Hae-Ryong Song; Harry M Fernandez; Jae-Hyuk Yang
Journal:  J Orthop Surg Res       Date:  2008-06-10       Impact factor: 2.359

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  2 in total

1.  Limitations of posterior spinal fusion to L5 for flaccid neuromuscular scoliosis focusing on pelvic obliquity.

Authors:  Wataru Saito; Gen Inoue; Eiki Shirasawa; Takayuki Imura; Toshiyuki Nakazawa; Masayuki Miyagi; Ayumu Kawakubo; Kentaro Uchida; Toshiaki Kotani; Tsutomu Akazawa; Masashi Takaso
Journal:  Spine Deform       Date:  2020-10-02

2.  Posterior spinal fusion to sacrum in non-ambulatory hypotonic neuromuscular patients: sacral rod/bone graft onlay method.

Authors:  Theresa Bui; Frederic Shapiro
Journal:  J Child Orthop       Date:  2014-04-13       Impact factor: 1.548

  2 in total

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