Literature DB >> 20213288

Reaction of isocyanides with thiophenols and gem-diactivated olefins: a one-pot synthesis of substituted 2-aminopyrroles.

Anna N Kolontsova1, Maria N Ivantsova, Maria I Tokareva, Maxim A Mironov.   

Abstract

A novel multicomponent reaction of isocyanides with thiophenols and gem-diactivated olefins has been discovered. Depending on the choice of isocyanides, substituted 2-aminopyrroles or thioimidates have been prepared. The obtained scaffolds bearing four points of diversity can directly be used in combinatorial syntheses.

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Year:  2010        PMID： 20213288     DOI： 10.1007/s11030-010-9233-x

Source DB:  PubMed          Journal:  Mol Divers        ISSN： 1381-1991            Impact factor:   2.943


  4 in total

1.  A planning strategy for diversity-oriented synthesis.

Authors:  Martin D Burke; Stuart L Schreiber
Journal:  Angew Chem Int Ed Engl       Date:  2004-01       Impact factor: 15.336

Review 2.  Recent developments in isocyanide based multicomponent reactions in applied chemistry.

Authors:  Alexander Dömling
Journal:  Chem Rev       Date:  2006-01       Impact factor: 60.622

3.  Synthesis and antiviral activity of some acyclic and C-acyclic pyrrolo[2,3-d]pyrimidine nucleoside analogues.

Authors:  S M Bennett; N Nguyen-Ba; K K Ogilvie
Journal:  J Med Chem       Date:  1990-08       Impact factor: 7.446

Review 4.  Isocyanide-based multicomponent reactions in drug discovery.

Authors:  Irini Akritopoulou-Zanze
Journal:  Curr Opin Chem Biol       Date:  2008-03-14       Impact factor: 8.822
  4 in total
  2 in total

Review 1.  Transition metal-free one-pot synthesis of nitrogen-containing heterocycles.

Authors:  Simpal Kumari; Dharma Kishore; Sarvesh Paliwal; Rajani Chauhan; Jaya Dwivedi; Aakanksha Mishra
Journal:  Mol Divers       Date:  2015-06-09       Impact factor: 2.943

Review 2.  Isocyanide-Based Multicomponent Reactions in Water: Advanced Green Tools for the Synthesis of Heterocyclic Compounds.

Authors:  Siamak Javanbakht; Mohammad Taghi Nazeri; Hassan Farhid; Tahereh Nasiriani; Vida Khodkari; Ahmad Shaabani
Journal:  Top Curr Chem (Cham)       Date:  2022-09-22
  2 in total

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