Literature DB >> 20212975

Stachybotrys chartarum (atra) contamination of the indoor environment: Health implications.

A Bitnun1, R M Nosal.   

Abstract

In 1998, widespread contamination of water-damaged school portables with the toxigenic mold Stachybotrys chartarum was detected in the province of Ontario. This mold may cause human disease through direct irritation, type 1 hypersensitivity or the production of toxins. A variety of respiratory, dermatological, eye and constitutional symptoms have been associated with heavy and prolonged exposure to S chartarum. S chartarum has also been potentially implicated as a rare cause of idiopathic pulmonary hemorrhage in infants. Ingestion of food heavily contaminated with toxin-producing molds, including S chartarum, can cause bone marrow suppression and immunotoxicity. However, the level of toxin exposure that occurs following inhalation of S chartarum is very low; consequently, serious adverse health effects from such an exposure are extremely unlikely. In a child with symptoms felt to be temporally related to the school environment, an assessment of the child's school should be carried out by the public health authorities so that potential irritants and allergens can be identified. Avoidance of exposure is the most effective mode of therapy. Buildings found to be heavily contaminated with molds, particularly S chartarum, should undergo thorough cleaning and repair to remove the offending agent(s), and prevent further water damage and mold overgrowth.

Entities:  

Keywords:  Fungus; Mold; Mycotoxin; Stachybotrys chartarum; Trichothecene

Year:  1999        PMID: 20212975      PMCID: PMC2828207          DOI: 10.1093/pch/4.2.125

Source DB:  PubMed          Journal:  Paediatr Child Health        ISSN: 1205-7088            Impact factor:   2.253


  11 in total

Review 1.  Health risk assessment of fungi in home environments.

Authors:  A P Verhoeff; H A Burge
Journal:  Ann Allergy Asthma Immunol       Date:  1997-06       Impact factor: 6.347

2.  Update: pulmonary hemorrhage/hemosiderosis among infants--Cleveland, Ohio, 1993-1996.

Authors: 
Journal:  MMWR Morb Mortal Wkly Rep       Date:  1997-01-17       Impact factor: 17.586

Review 3.  Stachybotrys, a mycotoxin-producing fungus of increasing toxicologic importance.

Authors:  F Fung; R Clark; S Williams
Journal:  J Toxicol Clin Toxicol       Date:  1998

4.  Experimental lung mycotoxicosis in mice induced by Stachybotrys atra.

Authors:  M Nikulin; K Reijula; B B Jarvis; E L Hintikka
Journal:  Int J Exp Pathol       Date:  1996-10       Impact factor: 1.925

5.  Bacteria, molds, and toxins in water-damaged building materials.

Authors:  M A Andersson; M Nikulin; U Köljalg; M C Andersson; F Rainey; K Reijula; E L Hintikka; M Salkinoja-Salonen
Journal:  Appl Environ Microbiol       Date:  1997-02       Impact factor: 4.792

6.  Acute pulmonary hemorrhage in infants associated with exposure to Stachybotrys atra and other fungi.

Authors:  R A Etzel; E Montaña; W G Sorenson; G J Kullman; T M Allan; D G Dearborn; D R Olson; B B Jarvis; J D Miller
Journal:  Arch Pediatr Adolesc Med       Date:  1998-08

Review 7.  A review of mycotoxins in indoor air.

Authors:  K M Hendry; E C Cole
Journal:  J Toxicol Environ Health       Date:  1993-02

8.  Respiratory health effects of home dampness and molds among Canadian children.

Authors:  R E Dales; H Zwanenburg; R Burnett; C A Franklin
Journal:  Am J Epidemiol       Date:  1991-07-15       Impact factor: 4.897

9.  Trichothecene mycotoxins in aerosolized conidia of Stachybotrys atra.

Authors:  W G Sorenson; D G Frazer; B B Jarvis; J Simpson; V A Robinson
Journal:  Appl Environ Microbiol       Date:  1987-06       Impact factor: 4.792

10.  Health and immunology study following exposure to toxigenic fungi (Stachybotrys chartarum) in a water-damaged office environment.

Authors:  E Johanning; R Biagini; D Hull; P Morey; B Jarvis; P Landsbergis
Journal:  Int Arch Occup Environ Health       Date:  1996       Impact factor: 3.015

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