Literature DB >> 20212948

Urine testing for Chlamydia trachomatis and hassle-free follow-up is acceptable to street youth.

A E McCarthy1, N E Macdonald, S Feder, J A Doherty, L McAvoy, B Toye.   

Abstract

OBJECTIVE: To evaluate whether street youth would use a sexually transmitted disease (STD) screening program involving non-nominal, noninvasive testing of urine for Chlamydia trachomatis with hassle-free follow-up and partner self-notification.
DESIGN: Cross-sectional pilot study in six centres frequented by street youth 13 to 25 years of age in the Regional Municipality of Ottawa-Carleton.
INTERVENTIONS: A structured, non-nominal face-to-face interview using an 88-item questionnaire was administered by a trained research assistant. Immediate feedback was provided to participants about specific individual risk reduction strategies for high risk life styles. Each street youth provided a urine sample that was tested non-nominally for C trachomatis by polymerase chain reaction (PCR). A single dose of azithromycin therapy was provided to participants who tested positive, each of whom was requested to encourage recent sexual partners to come forward for testing and treatment.
RESULTS: One hundred and sixty-three street youth were recruited (98 males and 65 females [male to female ratio 1.5:1]) over the four months of the study. The mean ages of participants were males 18.3+/-2.50 years and females 16.7+/-2.02 years. Ninety-two per cent (146) of all participants were sexually active and 99% of the sexually active youth (145 of 146) submitted urine samples. Urine samples were positive in 12 (8.2%) participants (seven males, five females), all of whom were asymptomatic. All those who tested positive were recruited from a single site (site specific rate 13.6%). Overall, only 25% of those tested returned spontaneously for test results; however, nine of 12 participants with positive results were treated due to investigator vigilance in locating the youth. Street youth partner self-notification resulted in five additional street youth requesting testing and treatment.
CONCLUSIONS: Street youth participated in a STD testing program when a street friendly program and noninvasive methods were used. Although more expensive, urine PCR testing increased program acceptance by street youth compared with previous local results. Detection of C trachomatis was high in this hard-to-reach population. There is a need to address further the problem of poor return rates for results and treatment, as well as low rates of partner notification.

Entities:  

Keywords:  Chlamydia trachomatis; Sexually transmitted diseases; Street youth

Year:  1999        PMID: 20212948      PMCID: PMC2827741          DOI: 10.1093/pch/4.6.395

Source DB:  PubMed          Journal:  Paediatr Child Health        ISSN: 1205-7088            Impact factor:   2.253


  7 in total

1.  Chlamydia infection in street youth: Need for more aggressive screening programs.

Authors:  R Tam; N Macdonald; S Feder; L Giglia; R Peeling; P Gully; B Toye; J Doherty
Journal:  Can J Infect Dis       Date:  1996-01

2.  Prevalence of sexually transmitted diseases in juvenile prostitutes and street youth.

Authors:  A C Rouget; J K Mah; R A Lang; M R Joffres
Journal:  Can J Infect Dis       Date:  1994-01

Review 3.  Molecular techniques for the laboratory identification of Chlamydia trachomatis.

Authors:  R W Peeling; R C Brunham
Journal:  J Int Fed Clin Chem       Date:  1994-06

4.  Canadian street youth: correlates of sexual risk-taking activity.

Authors:  N E MacDonald; W A Fisher; G A Wells; J A Doherty; W R Bowie
Journal:  Pediatr Infect Dis J       Date:  1994-08       Impact factor: 2.129

5.  Compliance with doxycycline therapy in sexually transmitted diseases clinics.

Authors:  M Augenbraun; L Bachmann; T Wallace; L Dubouchet; W McCormack; E W Hook
Journal:  Sex Transm Dis       Date:  1998-01       Impact factor: 2.830

6.  Diagnosis of Chlamydia trachomatis infections in asymptomatic men and women by PCR assay.

Authors:  B Toye; R W Peeling; P Jessamine; P Claman; I Gemmill
Journal:  J Clin Microbiol       Date:  1996-06       Impact factor: 5.948

7.  Direct detection of Chlamydia trachomatis in urine specimens from symptomatic and asymptomatic men by using a rapid polymerase chain reaction assay.

Authors:  G Jaschek; C A Gaydos; L E Welsh; T C Quinn
Journal:  J Clin Microbiol       Date:  1993-05       Impact factor: 5.948

  7 in total

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