| Literature DB >> 20210326 |
Yanfang Li1, Inken Plitzko, Janine Zaugg, Steffen Hering, Matthias Hamburger.
Abstract
A new dihydroisocoumarin was isolated from a dichloromethane extract of Haloxylon scoparium with the aid of a functional assay with Xenopus oocytes transiently expressing GABA(A) receptors of defined subunit composition (alpha(1)beta(2)gamma(2S)). Compound 1 induced a maximum potentiation of the chloride currents by 144.6 +/- 35.3% with an EC(50) of 140.2 +/- 51.2 muM.Entities:
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Year: 2010 PMID： 20210326 DOI： 10.1021/np900803w
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050