Literature DB >> 20209566

Molecular editing of kinase-targeting resorcylic acid lactones (RAL): Fluoroenone RAL.

Rajamalleswaramma Jogireddy1, Sofia Barluenga, Nicolas Winssinger.   

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Year:  2010        PMID： 20209566     DOI： 10.1002/cmdc.201000047

Source DB:  PubMed          Journal:  ChemMedChem        ISSN： 1860-7179            Impact factor:   3.466


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  7 in total

1.  Total synthesis of LL-Z1640-2 utilizing a late-stage intramolecular Nozaki-Hiyama-Kishi reaction.

Authors:  Christopher A Leclair; Matthew B Boxer; Craig J Thomas; David J Maloney
Journal:  Tetrahedron Lett       Date:  2010-12-29       Impact factor: 2.415

2.  Kinase inhibition by deoxy analogues of the resorcylic lactone L-783277.

Authors:  Marc Liniger; Christian Neuhaus; Tatjana Hofmann; Luca Fransioli-Ignazio; Michel Jordi; Peter Drueckes; Jörg Trappe; Doriano Fabbro; Karl-Heinz Altmann
Journal:  ACS Med Chem Lett       Date:  2010-10-20       Impact factor: 4.345

3.  Exploring aigialomycin d and its analogues as protein kinase inhibitors for cancer targets.

Authors:  Jin Xu; Anqi Chen; Mei-Lin Go; Kassoum Nacro; Boping Liu; Christina L L Chai
Journal:  ACS Med Chem Lett       Date:  2011-07-17       Impact factor: 4.345

4.  Covalent Modifiers: A Chemical Perspective on the Reactivity of α,β-Unsaturated Carbonyls with Thiols via Hetero-Michael Addition Reactions.

Authors:  Paul A Jackson; John C Widen; Daniel A Harki; Kay M Brummond
Journal:  J Med Chem       Date:  2016-12-20       Impact factor: 7.446

5.  Stereodefined alkenes with a fluoro-chloro terminus as a uniquely enabling compound class.

Authors:  Qinghe Liu; Yucheng Mu; Tobias Koengeter; Richard R Schrock; Amir H Hoveyda
Journal:  Nat Chem       Date:  2022-02-17       Impact factor: 24.274

6.  Isolation, semisynthesis, covalent docking and transforming growth factor beta-activated kinase 1 (TAK1)-inhibitory activities of (5Z)-7-oxozeaenol analogues.

Authors:  Lara Fakhouri; Tamam El-Elimat; Dow P Hurst; Patricia H Reggio; Cedric J Pearce; Nicholas H Oberlies; Mitchell P Croatt
Journal:  Bioorg Med Chem       Date:  2015-09-25       Impact factor: 3.461

7.  Media and strain studies for the scaled production of cis-enone resorcylic acid lactones as feedstocks for semisynthesis.

Authors:  Zeinab Y Al Subeh; Huzefa A Raja; Jennifer C Obike; Cedric J Pearce; Mitchell P Croatt; Nicholas H Oberlies
Journal:  J Antibiot (Tokyo)       Date:  2021-06-21       Impact factor: 3.424
  7 in total

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