Literature DB >> 20209400

[Fournier's gangrene: analysis of risk factors affecting the prognosis and cost of therapy in 18 cases].

Hakan Canbaz1, Mehmet Cağlikülekçi, Uğur Altun, Musa Dirlik, Ozgür Türkmenoğlu, Bahar Taşdelen, Süha Aydin.   

Abstract

BACKGROUND: Fournier's gangrene (FG) is a rapidly progressive, polymicrobial, synergistic necrotizing fasciitis, and the mortality rate is still high. We aimed to determine the risk factors affecting prognosis and treatment cost.
METHODS: Eighteen patients operated for FG during 2003-2007 were investigated retrospectively. Surviving and exitus groups were compared regarding demographic data, etiological factors, laboratory findings, treatment modality, length of hospital stay, and treatment cost.
RESULTS: Mean age was 54.5 years, and the female/male ratio was 6/12. Mortality was observed in 6 (33.3%) patients and was significantly high among females (66.6%) (p=0.035). Mean duration of complaint in the exitus group (9+/-3 days) was higher than in survivors (5+/-3 days) (p=0.018). The most frequent comorbid disease was diabetes (39.2%), the most frequent etiology was perianal abscess (55.6%) and the primary location of infection was anorectal region (61.1%). Hyponatremia was significantly high in surviving patients (p=0.039). Mean of FG severity point in the exitus group (6.83) was higher than in survivors (3.17) (p=0.011). The most frequently cultivated microorganism, Escherichia coli (66.6%), was significantly high in the exitus group (p=0.012). The mean number of debridements was 4.67. Fecal diversion was performed in 7 (38.8%) patients. Hospital stay in the surviving group (34.17 days) was higher than in the exitus group (10.50 days) (p=0.002). Treatment cost between groups was indifferent (p>0.05).
CONCLUSION: Female gender, duration of complaint, FG severity point, and cultivated microorganism (E. Coli) were thought to affect mortality. FG is a disease that might cause extended hospital stay and high treatment cost.

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Year:  2010        PMID: 20209400

Source DB:  PubMed          Journal:  Ulus Travma Acil Cerrahi Derg


  3 in total

1.  Evaluation of factors affecting mortality in Fournier's Gangrene: Retrospective clinical study of sixteen cases.

Authors:  Erkan Oymacı; Ali Coşkun; Savaş Yakan; Nazif Erkan; Ahmet Deniz Uçar; Mehmet Yıldırım
Journal:  Ulus Cerrahi Derg       Date:  2014-06-01

2.  Laboratory Risk Indicators for Necrotizing Fasciitis and Associations with Mortality.

Authors:  Elif Colak; Nuraydin Ozlem; Gultekin Ozan Kucuk; Recep Aktimur; Sadik Kesmer
Journal:  Turk J Emerg Med       Date:  2016-02-26

3.  Fournier's gangrene: Causes, presentation and survival of sixty-five patients.

Authors:  Kerem Taken; Mehmet Resit Oncu; Muslum Ergun; Recep Eryilmaz; Canser Yilmaz Demir; Murat Demir; Mustafa Gunes
Journal:  Pak J Med Sci       Date:  2016 May-Jun       Impact factor: 1.088

  3 in total

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