Literature DB >> 20207350

Common genetic variation in MTNR1B is associated with serum testosterone, glucose tolerance, and insulin secretion in polycystic ovary syndrome patients.

Lei Wang1, Ying Wang, Xiaoping Zhang, Juanzi Shi, Min Wang, Zhiyun Wei, Aman Zhao, Baojie Li, Xinzhi Zhao, Qinghe Xing, Lin He.   

Abstract

Melatonin plays an important role in many aspects of the human reproductive process. Our results first strongly suggest that MTNR1B mediating some functions of melatonin contributes to the phenotypic expression of polycystic ovary syndrome, which provide a new insight into the role of MTNR1B gene in the pathophysiology of the disease. Crown
Copyright © 2010. Published by Elsevier Inc. All rights reserved.

Entities:  

Mesh：

Substances：

Year:  2010        PMID： 20207350     DOI： 10.1016/j.fertnstert.2010.01.059

Source DB:  PubMed          Journal:  Fertil Steril        ISSN： 0015-0282            Impact factor:   7.329


  8 in total

1.  Polycystic ovary syndrome is not associated with genetic variants that mark risk of type 2 diabetes.

Authors:  R Saxena; C K Welt
Journal:  Acta Diabetol       Date:  2012-03-03       Impact factor: 4.280

2.  Melatonin pathway genes and breast cancer risk among Chinese women.

Authors:  Sandra L Deming; Wei Lu; Alicia Beeghly-Fadiel; Ying Zheng; Qiuyin Cai; Jirong Long; Xiao Ou Shu; Yu-Tang Gao; Wei Zheng
Journal:  Breast Cancer Res Treat       Date:  2011-12-03       Impact factor: 4.872

3.  Common genetic variation in CYP1B1 is associated with concentrations of T₄, FT₃ and FT₄ in the sera of polycystic ovary syndrome patients.

Authors:  Shien Zou; Qing Sang; Huan Wang; Ruizhi Feng; Qiaoli Li; Xinzhi Zhao; Qinghe Xing; Li Jin; Lin He; Lei Wang
Journal:  Mol Biol Rep       Date:  2013-01-03       Impact factor: 2.316

Review 4.  The role of melatonin in polycystic ovary syndrome: A review.

Authors:  Sina Mojaverrostami; Narjes Asghari; Mahsa Khamisabadi; Heidar Heidari Khoei
Journal:  Int J Reprod Biomed       Date:  2019-12-30

Review 5.  Membrane Melatonin Receptors Activated Cell Signaling in Physiology and Disease.

Authors:  Georgi Nikolaev; Ralitsa Robeva; Rossitza Konakchieva
Journal:  Int J Mol Sci       Date:  2021-12-31       Impact factor: 5.923

Review 6.  The Polycystic Ovary Syndrome and the Metabolic Syndrome: A Possible Chronobiotic-Cytoprotective Adjuvant Therapy.

Authors:  Eduardo Spinedi; Daniel P Cardinali
Journal:  Int J Endocrinol       Date:  2018-07-25       Impact factor: 3.257

7.  Association between melatonin receptor gene polymorphisms and polycystic ovarian syndrome: a systematic review and meta-analysis.

Authors:  Shiqi Yi; Jiawei Xu; Hao Shi; Wenbo Li; Qian Li; Ying-Pu Sun
Journal:  Biosci Rep       Date:  2020-06-26       Impact factor: 3.840

Review 8.  Pathophysiologic Mechanisms of Insulin Secretion and Signaling-Related Genes in Etiology of Polycystic Ovary Syndrome.

Authors:  Zahra Shaaban; Arezoo Khoradmehr; Amir Amiri-Yekta; Fariborz Nowzari; Mohammad Reza Jafarzadeh Shirazi; Amin Tamadon
Journal:  Genet Res (Camb)       Date:  2021-12-06       Impact factor: 1.588
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.