Literature DB >> 20207318

Comparison of standard-dose and reduced-dose expiratory MDCT techniques for assessment of tracheomalacia in children.

Edward Y Lee1, Keith J Strauss, Donald A Tracy, Maria d'Almeida Bastos, David Zurakowski, Phillip M Boiselle.   

Abstract

RATIONALE AND
OBJECTIVES: The aim of this study was to assess the effects of radiation dose reduction on the assessment of the tracheal lumen on expiratory multidetector computed tomographic (MDCT) images of pediatric patients referred for evaluation for tracheomalacia (TM).
MATERIALS AND METHODS: The hospital information system was used to retrospectively identify 20 standard-dose and 20 reduced-dose paired inspiratory and expiratory MDCT studies performed for the evaluation of suspected TM in pediatric patients (aged <or= 18 years). The reduced-dose technique used a 50% reduction of the tube current for the expiratory portion of the study compared to the standard-dose technique. Two experienced pediatric radiologists, who were blinded to the tube current of the study, reported their levels of confidence for measuring the tracheal lumen using a four-point scale ranging from zero (no confidence) to three (highest level of confidence). The difference in confidence level between the two groups of studies was analyzed using the Mann-Whitney U test. The percentage of radiation dose reduction using the reduced-dose technique in comparison to the standard-dose technique was estimated using anthropomorphic thorax phantoms. The presence or absence of TM (>or=50% expiratory reduction in tracheal cross-sectional luminal area) on MDCT imaging was compared to bronchoscopic results for the subset of 32 patients who underwent both procedures.
RESULTS: A high level of confidence was reported for measuring the tracheal lumen on MDCT imaging for both standard-dose (median, 3.0) and reduced-dose (median, 3.0) expiratory sequences (P = .80). The total radiation dose of the paired inspiratory-expiratory computed tomographic (CT) exam was decreased by 23% with the reduced-dose technique. TM was diagnosed by CT imaging in seven patients who underwent standard-dose and six patients who underwent reduced-dose paired inspiratory and expiratory MDCT studies. CT results for the presence or absence of TM were concordant with the results of bronchoscopy in all 32 patients who underwent both procedures.
CONCLUSION: The radiation dose of paired inspiratory-expiratory CT imaging can be reduced by 23% while maintaining similar diagnostic confidence for assessment of the tracheal lumen compared to a standard-dose technique in pediatric patients. Thus, a reduced-dose technique is recommended for evaluating TM in children. Copyright 2010 AUR. Published by Elsevier Inc. All rights reserved.

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Year:  2010        PMID: 20207318     DOI: 10.1016/j.acra.2009.11.014

Source DB:  PubMed          Journal:  Acad Radiol        ISSN: 1076-6332            Impact factor:   3.173


  8 in total

1.  Advanced large airway CT imaging in children: evolution from axial to 4-D assessment.

Authors:  Edward Y Lee; Evan J Zucker; Ricardo Restrepo; Pedro Daltro; Phillip M Boiselle
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2.  Free-breathing cine CT for the diagnosis of tracheomalacia in young children.

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Journal:  Pediatr Radiol       Date:  2013-02-17

3.  Dynamic PEEP Study: A Non-invasive Diagnostic Exam to Assess for Effective PEEP in Children with Severe BPD.

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Review 4.  Lung and large airway imaging: magnetic resonance imaging versus computed tomography.

Authors:  Mark C Liszewski; Pierluigi Ciet; Abbey J Winant; Edward Y Lee
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Review 5.  Interstitial lung disease in infants: new classification system, imaging technique, clinical presentation and imaging findings.

Authors:  Edward Y Lee
Journal:  Pediatr Radiol       Date:  2012-11-15

6.  Ultrashort Echo-Time MRI for the Assessment of Tracheomalacia in Neonates.

Authors:  Erik B Hysinger; Alister J Bates; Nara S Higano; Dan Benscoter; Robert J Fleck; Catherine K Hart; Gregory Burg; Alessandro De Alarcon; Paul S Kingma; Jason C Woods
Journal:  Chest       Date:  2019-12-17       Impact factor: 9.410

7.  Tracheal collapse diagnosed by multidetector computed tomography: evaluation of different image analysis methods.

Authors:  Mette Nygaard; Elisabeth Bendstrup; Ronald Dahl; Ole Hilberg; Finn Rasmussen
Journal:  Eur Clin Respir J       Date:  2017-12-08

8.  Technique, pitfalls, quality, radiation dose and findings of dynamic 4-dimensional computed tomography for airway imaging in infants and children.

Authors:  Savvas Andronikou; Mark Chopra; Simon Langton-Hewer; Pia Maier; Jon Green; Emma Norbury; Sarah Price; Mary Smail
Journal:  Pediatr Radiol       Date:  2019-01-25
  8 in total

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