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Literature DB >> 20206280

Mgat1-dependent N-glycans are essential for the normal development of both vertebrate and invertebrate metazoans.

Abstract

UDP-GlcNAc:alpha3-D-mannoside beta1,2-N-acetylglucosaminyltransferase I (GnTI, encoded by Mgat1) first appeared in evolution at about the same time as metazoa suggesting that GnTI-dependent glycans are essential for the development of multicellular organisms. This review describes the effects of mutations in the Mgat1 gene on the development of Caenorhabditis elegans, Drosophila melanogaster and mice. Copyright 2010 Elsevier Ltd. All rights reserved.

Entities: Chemical Gene Species

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Year: 2010 PMID： 20206280 DOI： 10.1016/j.semcdb.2010.02.010

Source DB: PubMed Journal: Semin Cell Dev Biol ISSN： 1084-9521 Impact factor: 7.727

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Cited

19 in total

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3. Multiple members of the UDP-GalNAc: polypeptide N-acetylgalactosaminyltransferase family are essential for viability in Drosophila.

Authors: Duy T Tran; Liping Zhang; Ying Zhang; E Tian; Lesley A Earl; Kelly G Ten Hagen
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Review 6. Host glycans and antigen presentation.

Authors: Sean O Ryan; Brian A Cobb
Journal: Microbes Infect Date: 2012-04-22 Impact factor: 2.700

7. N-glycosylation requirements in neuromuscular synaptogenesis.

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Review 8. The role of protein N-glycosylation in neural transmission.

Authors: Hilary Scott; Vladislav M Panin
Journal: Glycobiology Date: 2014-03-18 Impact factor: 4.313

9. Ablation of N-acetylglucosaminyltransferases in Caenorhabditis induces expression of unusual intersected and bisected N-glycans.

Authors: Shi Yan; Huijie Wang; Harry Schachter; Chunsheng Jin; Iain B H Wilson; Katharina Paschinger
Journal: Biochim Biophys Acta Gen Subj Date: 2018-07-05 Impact factor: 3.770

10. Mgat1-dependent N-glycosylation of membrane components primes Drosophila melanogaster blood cells for the cellular encapsulation response.

Authors: Nathan T Mortimer; Balint Z Kacsoh; Erin S Keebaugh; Todd A Schlenke
Journal: PLoS Pathog Date: 2012-07-19 Impact factor: 6.823