Literature DB >> 20205503

Assessment of normal bowel habits in the general adult population: the Popcol study.

Susanna A Walter1, Lars Kjellström, Henry Nyhlin, Nicholas J Talley, Lars Agréus.   

Abstract

OBJECTIVE: Defining normal stool habit is important when evaluating diarrhoea or constipation, but common confounders such as irritable bowel syndrome (IBS) or the intake of medications with gastrointestinal side effects have not been considered in earlier population based studies defining what is normal. We hypothesized that the exclusion of subjects with common confounders would help to better understand what are "normal bowel habits". We aimed to prospectively study bowel habits in a carefully studied random sample of the general population.
MATERIAL AND METHODS: Two hundred and sixty-eight randomly selected subjects between 18 and 70 years completed symptom diaries for one week and were clinically evaluated by a gastroenterologist. They also had a colonoscopy and laboratory investigations to exclude organic disease.
RESULTS: One hundred and twenty-four subjects had no organic gastrointestinal abnormality, IBS, or relevant medication; 98% of them had between three stools per day and three per week. Seventy-seven percent of all stools were normal, 12% hard, and 10% loose in consistency. Urgency was reported by 36%; straining by 47% and incomplete defecation by 46%. After the exclusion of subjects with organic abnormalities, women had significantly more symptoms than men in terms of abdominal pain, bloating, constipation, urgency, and feeling of incomplete evacuation but these gender differences disappeared after excluding subjects with IBS.
CONCLUSIONS: This study confirms that normal stool frequency is between three per week and three per day. We could not demonstrate any gender or age differences in terms of stool frequency, defecatory symptoms or abdominal bloating. Some degree of urgency, straining, and incomplete evacuation should be considered normal.

Entities:  

Mesh:

Year:  2010        PMID: 20205503     DOI: 10.3109/00365520903551332

Source DB:  PubMed          Journal:  Scand J Gastroenterol        ISSN: 0036-5521            Impact factor:   2.423


  20 in total

1.  IBS patients show frequent fluctuations between loose/watery and hard/lumpy stools: implications for treatment.

Authors:  Olafur S Palsson; Jeffrey S Baggish; Marsha J Turner; William E Whitehead
Journal:  Am J Gastroenterol       Date:  2011-11-08       Impact factor: 10.864

2.  Efficacy and Safety of Tenapanor in Patients with Hyperphosphatemia Receiving Maintenance Hemodialysis: A Randomized Phase 3 Trial.

Authors:  Geoffrey A Block; David P Rosenbaum; Andrew Yan; Glenn M Chertow
Journal:  J Am Soc Nephrol       Date:  2019-03-07       Impact factor: 10.121

3.  Difficult defecation in constipated patients and its relationship to colonic disorders.

Authors:  Michel Bouchoucha; Ghislain Devroede; Cyriaque Bon; Florence Mary; Baktiar Bejou; Robert Benamouzig
Journal:  Int J Colorectal Dis       Date:  2016-02-09       Impact factor: 2.571

4.  The Impact of Diagnostic Status on Quality of Life in Irritable Bowel Syndrome.

Authors:  Gillian Eleanor Cassar; George Youssef J; Simon R Knowles; Richard Moulding; David Austin
Journal:  Turk J Gastroenterol       Date:  2021-10       Impact factor: 1.555

5.  A simple bowel habit score for colorectal patients.

Authors:  Roberto Zinicola; N Cracco; A Totaro; Raffaele Dalla Valle; G Pedrazzi
Journal:  Int J Colorectal Dis       Date:  2016-10-17       Impact factor: 2.571

6.  Changes in bowel symptoms 1 year after rectocele repair.

Authors:  Vivian W Sung; Charles R Rardin; Christina A Raker; Christine A LaSala; Deborah L Myers
Journal:  Am J Obstet Gynecol       Date:  2012-06-29       Impact factor: 8.661

7.  Female-Specific Association Between Variants on Chromosome 9 and Self-Reported Diagnosis of Irritable Bowel Syndrome.

Authors:  Ferdinando Bonfiglio; Tenghao Zheng; Koldo Garcia-Etxebarria; Fatemeh Hadizadeh; Luis Bujanda; Francesca Bresso; Lars Agreus; Anna Andreasson; Aldona Dlugosz; Greger Lindberg; Peter T Schmidt; Pontus Karling; Bodil Ohlsson; Magnus Simren; Susanna Walter; Gerardo Nardone; Rosario Cuomo; Paolo Usai-Satta; Francesca Galeazzi; Matteo Neri; Piero Portincasa; Massimo Bellini; Giovanni Barbara; Anna Latiano; Matthias Hübenthal; Vincent Thijs; Mihai G Netea; Daisy Jonkers; Lin Chang; Emeran A Mayer; Mira M Wouters; Guy Boeckxstaens; Michael Camilleri; Andre Franke; Alexandra Zhernakova; Mauro D'Amato
Journal:  Gastroenterology       Date:  2018-04-05       Impact factor: 22.682

Review 8.  Understanding the physiology of human defaecation and disorders of continence and evacuation.

Authors:  Paul T Heitmann; Paul F Vollebregt; Charles H Knowles; Peter J Lunniss; Phil G Dinning; S Mark Scott
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2021-08-09       Impact factor: 46.802

9.  Functional variants in the sucrase-isomaltase gene associate with increased risk of irritable bowel syndrome.

Authors:  Maria Henström; Lena Diekmann; Ferdinando Bonfiglio; Fatemeh Hadizadeh; Eva-Maria Kuech; Maren von Köckritz-Blickwede; Louise B Thingholm; Tenghao Zheng; Ghazaleh Assadi; Claudia Dierks; Martin Heine; Ute Philipp; Ottmar Distl; Mary E Money; Meriem Belheouane; Femke-Anouska Heinsen; Joseph Rafter; Gerardo Nardone; Rosario Cuomo; Paolo Usai-Satta; Francesca Galeazzi; Matteo Neri; Susanna Walter; Magnus Simrén; Pontus Karling; Bodil Ohlsson; Peter T Schmidt; Greger Lindberg; Aldona Dlugosz; Lars Agreus; Anna Andreasson; Emeran Mayer; John F Baines; Lars Engstrand; Piero Portincasa; Massimo Bellini; Vincenzo Stanghellini; Giovanni Barbara; Lin Chang; Michael Camilleri; Andre Franke; Hassan Y Naim; Mauro D'Amato
Journal:  Gut       Date:  2016-11-21       Impact factor: 23.059

Review 10.  The epidemiology of irritable bowel syndrome.

Authors:  Caroline Canavan; Joe West; Timothy Card
Journal:  Clin Epidemiol       Date:  2014-02-04       Impact factor: 4.790

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.