Literature DB >> 20204200

Non-alpha-hydroxylated aldehydes with evolved transketolase enzymes.

Armando Cázares1, James L Galman, Lydia G Crago, Mark E B Smith, John Strafford, Leonardo Ríos-Solís, Gary J Lye, Paul A Dalby, Helen C Hailes.   

Abstract

Transketolase mutants previously identified for use with the non-phosphorylated aldehyde propanal have been explored with a series of linear and cyclic aliphatic aldehydes, and excellent stereoselectivities observed.

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Year:  2010        PMID: 20204200     DOI: 10.1039/b924144b

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN: 1477-0520            Impact factor:   3.876


  9 in total

1.  Lyme disease spirochaete Borrelia burgdorferi does not require thiamin.

Authors:  Kai Zhang; Jiang Bian; Yijie Deng; Alexis Smith; Roy E Nunez; Michael B Li; Utpal Pal; Ai-Ming Yu; Weigang Qiu; Steven E Ealick; Chunhao Li
Journal:  Nat Microbiol       Date:  2016-11-21       Impact factor: 17.745

2.  Droplet millifluidics for kinetic study of transketolase.

Authors:  A Pinsolle; F Charmantray; L Hecquet; F Sarrazin
Journal:  Biomicrofluidics       Date:  2016-11-10       Impact factor: 2.800

3.  Directed evolution to re-adapt a co-evolved network within an enzyme.

Authors:  John Strafford; Panwajee Payongsri; Edward G Hibbert; Phattaraporn Morris; Sukhjeet S Batth; David Steadman; Mark E B Smith; John M Ward; Helen C Hailes; Paul A Dalby
Journal:  J Biotechnol       Date:  2011-11-29       Impact factor: 3.307

4.  Structural Analysis of an Evolved Transketolase Reveals Divergent Binding Modes.

Authors:  Pierre E Affaticati; Shao-Bo Dai; Panwajee Payongsri; Helen C Hailes; Kai Tittmann; Paul A Dalby
Journal:  Sci Rep       Date:  2016-10-21       Impact factor: 4.379

5.  Two strategies to engineer flexible loops for improved enzyme thermostability.

Authors:  Haoran Yu; Yihan Yan; Cheng Zhang; Paul A Dalby
Journal:  Sci Rep       Date:  2017-02-01       Impact factor: 4.379

6.  Separating Thermodynamics from Kinetics-A New Understanding of the Transketolase Reaction.

Authors:  Stefan R Marsden; Lorina Gjonaj; Stephen J Eustace; Ulf Hanefeld
Journal:  ChemCatChem       Date:  2017-04-13       Impact factor: 5.686

7.  Biophysical characterization of the inactivation of E. coli transketolase by aqueous co-solvents.

Authors:  Phattaraporn Morris; Ribia García-Arrazola; Leonardo Rios-Solis; Paul A Dalby
Journal:  Sci Rep       Date:  2021-12-08       Impact factor: 4.379

Review 8.  Synthetic biology for the directed evolution of protein biocatalysts: navigating sequence space intelligently.

Authors:  Andrew Currin; Neil Swainston; Philip J Day; Douglas B Kell
Journal:  Chem Soc Rev       Date:  2015-03-07       Impact factor: 54.564

9.  Assessing the Thiamine Diphosphate Dependent Pyruvate Dehydrogenase E1 Subunit for Carboligation Reactions with Aliphatic Ketoacids.

Authors:  Stefan R Marsden; Duncan G G McMillan; Ulf Hanefeld
Journal:  Int J Mol Sci       Date:  2020-11-16       Impact factor: 5.923

  9 in total

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