Literature DB >> 20202179

The PROTON study: profiles of blood product transfusion recipients in the Netherlands.

B A Borkent-Raven1, M P Janssen, C L van der Poel, W P Schaasberg, G J Bonsel, B A van Hout.   

Abstract

BACKGROUND: Transfusion recipient data are needed for correct estimation of cost-effectiveness in terms of recipient outcomes after transfusion. Also, such data are essential for monitoring blood use, estimation of future blood use and benchmarking. STUDY DESIGN AND METHODS: A sample of 20 of 93 Dutch hospitals was selected. Datasets containing all blood product transfusions between 1996 and 2006 were extracted from hospital blood bank computer systems, containing transfusion date, blood product type and recipient characteristics such as gender, address, date of birth. The datasets were appended and matched to national hospitalization datasets including primary discharge diagnoses (ICD-9). Using these data, we estimated distributions of blood recipient characteristics in the Netherlands.
RESULTS: The dataset contains information on 290,043 patients who received 2,405,012 blood products (1,720,075 RBC, 443,697 FFP, 241,240 PLT) from 1996 to 2006. This is 28% of total blood use in the Netherlands during this period. Comparable diagnosis and age distributions of all hospitalizations indicate included hospitals to be representative, per hospital category, for the Netherlands. Of all red blood cells (RBC), fresh-frozen plasma (FFP) and platelets (PLT), respectively 1.7%, 2.5% and 4.5% were transfused to neonates. Recipients of 65 years or older received 57.6% of RBC, 41.4% of FFP and 29.0% of PLT. Most of the blood products were transfused to patients with diseases of the circulary system (25.1%) or neoplasms (22.0%).
CONCLUSION: Transfusion data from a limited sample of hospitals can be used to estimate national distributions of blood recipient characteristics.

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Year:  2010        PMID: 20202179     DOI: 10.1111/j.1423-0410.2010.01312.x

Source DB:  PubMed          Journal:  Vox Sang        ISSN: 0042-9007            Impact factor:   2.144


  15 in total

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Authors:  Nyashadzaishe Mafirakureva; Star Khoza; Oliver Hassall; Brian E Faragher; Isaac Kajja; David A Mvere; Jean C Emmanuel; Maarten J Postma; Marinus van Hulst
Journal:  Blood Transfus       Date:  2015-07-15       Impact factor: 3.443

Review 2.  Restrictive versus liberal red blood cell transfusion strategies for people with haematological malignancies treated with intensive chemotherapy or radiotherapy, or both, with or without haematopoietic stem cell support.

Authors:  Lise J Estcourt; Reem Malouf; Marialena Trivella; Dean A Fergusson; Sally Hopewell; Michael F Murphy
Journal:  Cochrane Database Syst Rev       Date:  2017-01-27

3.  Red blood cell use in Switzerland: trends and demographic challenges.

Authors:  Thomas Volken; Andreas Buser; Damiano Castelli; Stefano Fontana; Beat M Frey; Ilka Rüsges-Wolter; Amira Sarraj; Jörg Sigle; Jutta Thierbach; Tina Weingand; Behrouz Mansouri Taleghani
Journal:  Blood Transfus       Date:  2016-09-30       Impact factor: 3.443

4.  Retrospective Analysis of the Blood Component Utilization in a University Hospital of Maximum Medical Care.

Authors:  R Georg Geißler; Dominik Franz; Hubert Buddendick; Petra Krakowitzky; Holger Bunzemeier; Norbert Roeder; Hugo Van Aken; Torsten Kessler; Wolfgang Berdel; Walter Sibrowski; Peter Schlenke
Journal:  Transfus Med Hemother       Date:  2012-03-22       Impact factor: 3.747

5.  Utilisation of blood components in cardiac surgery: a single-centre retrospective analysis with regard to diagnosis-related procedures.

Authors:  Raoul Georg Geissler; Heinrich Rotering; Hubert Buddendick; Dominik Franz; Holger Bunzemeier; Norbert Roeder; Robert Kwiecien; Walter Sibrowski; Hans H Scheld; Sven Martens; Peter Schlenke
Journal:  Transfus Med Hemother       Date:  2015-03-20       Impact factor: 3.747

6.  Monitoring compliance with transfusion guidelines in hospital departments by electronic data capture.

Authors:  Astrid Norgaard; Trine Honnens De Lichtenberg; Jens Nielsen; Pär I Johansson
Journal:  Blood Transfus       Date:  2014-06-05       Impact factor: 3.443

7.  Demographic and epidemiologic characterization of transfusion recipients from four US regions: evidence from the REDS-III recipient database.

Authors:  Matthew S Karafin; Roberta Bruhn; Matt Westlake; Marian T Sullivan; Walter Bialkowski; Gustaf Edgren; Nareg H Roubinian; Ronald G Hauser; Daryl J Kor; Debra Fleischmann; Jerome L Gottschall; Edward L Murphy; Darrell J Triulzi
Journal:  Transfusion       Date:  2017-10-24       Impact factor: 3.157

8.  Population-Based Analysis of the Impact of Demographics on the Current and Future Blood Supply in the Saarland.

Authors:  Hermann Eichler; Anna Katharina Feyer; Kerstin Weitmann; Wolfgang Hoffmann; Olaf Henseler; Andreas Opitz; Alexander Patek; Detlef Nikolaus Hans; Linda Schönborn; Andreas Greinacher
Journal:  Transfus Med Hemother       Date:  2020-12-23       Impact factor: 3.747

9.  Clinical effects of blood donor characteristics in transfusion recipients: protocol of a framework to study the blood donor-recipient continuum.

Authors:  Michaël Chassé; Lauralyn McIntyre; Alan Tinmouth; Jason Acker; Shane W English; Greg Knoll; Alan Forster; Nadine Shehata; Kumanan Wilson; Carl van Walraven; Robin Ducharme; Dean A Fergusson
Journal:  BMJ Open       Date:  2015-01-19       Impact factor: 2.692

10.  Characteristics of Recipients of Red Blood Cell Concentrates in a German Federal State.

Authors:  Linda Schönborn; Kerstin Weitmann; Andreas Greinacher; Wolfgang Hoffmann
Journal:  Transfus Med Hemother       Date:  2020-09-22       Impact factor: 3.747

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