| Literature DB >> 20199845 |
Beatrice Nico1, Domenico Ribatti.
Abstract
The aquaporins (AQPs) are a family of transmembrane water channel proteins widely distributed and play a major role in transcellular and transepithelial water movement. Moreover, recent evidence indicates that AQPs may be involved in cell migration and angiogenesis. This review article summarizes literature data concerning the involvement of AQPs in tumor growth, angiogenesis and metastatic process and suggest a potential therapeutic approach by antagonizing their biological activity. Copyright 2010 Elsevier Ireland Ltd. All rights reserved.Entities:
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Year: 2010 PMID： 20199845 DOI： 10.1016/j.canlet.2010.02.005
Source DB: PubMed Journal: Cancer Lett ISSN： 0304-3835 Impact factor: 8.679