Literature DB >> 20198358

[Medication dependency and physician's role].

R Holzbach1, M Martens, J Kalke, P Raschke.   

Abstract

The administration of benzodiazepines in suicidal, anxious, or agitated patients with depression is common international practice. Nevertheless, the prescription of BZDs is recommended to be limited to a period of a few weeks. There are several epidemiological studies about the situation in Germany, but many questions are still unanswered. The BfArM sought a new method to track prescription of medications with the risk to induce dependency. The present article describes the methodology and the early results of the pilot study. As a new approach, data from a processing center for pharmacies were used; patient-years, a risk scale with six steps, and diazepam-equivalence dose instead of defined daily dose were used for the analysis. About 35% of prescriptions were long-term treatment. Even if several physicians prescribe the medication, the main physician prescribing the medication can identify the risk level of the patient in 80-90% of cases.

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Year:  2010        PMID: 20198358     DOI: 10.1007/s00103-010-1029-8

Source DB:  PubMed          Journal:  Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz        ISSN: 1436-9990            Impact factor:   1.513


  6 in total

Review 1.  The problems of long-term treatment with benzodiazepines and related substances.

Authors:  Katrin Janhsen; Patrik Roser; Knut Hoffmann
Journal:  Dtsch Arztebl Int       Date:  2015-01-05       Impact factor: 5.594

2.  Problematic Medication With Benzodiazepines, "Z-drugs", and Opioid Analgesics.

Authors:  Sven Buth; Rüdiger Holzbach; Marcus-Sebastian Martens; Eike Neumann-Runde; Ommo Meiners; Uwe Verthein
Journal:  Dtsch Arztebl Int       Date:  2019-09-13       Impact factor: 5.594

3.  Evaluation of a hospital-based day-structuring exercise programme on exacerbated behavioural and psychological symptoms in dementia--the exercise carrousel: study protocol for a randomised controlled trial.

Authors:  Tim Fleiner; Wiebren Zijlstra; Hannah Dauth; Peter Haussermann
Journal:  Trials       Date:  2015-05-26       Impact factor: 2.279

4.  Prominent physical inactivity in acute dementia care: Psychopathology seems to be more important than the dose of sedative medication.

Authors:  Tim Fleiner; Marleen Gersie; Sayantan Ghosh; Sabato Mellone; Wiebren Zijlstra; Peter Haussermann
Journal:  Int J Geriatr Psychiatry       Date:  2018-11-27       Impact factor: 3.485

5.  Structured physical exercise improves neuropsychiatric symptoms in acute dementia care: a hospital-based RCT.

Authors:  Tim Fleiner; Hannah Dauth; Marleen Gersie; Wiebren Zijlstra; Peter Haussermann
Journal:  Alzheimers Res Ther       Date:  2017-08-29       Impact factor: 6.982

Review 6.  Benzodiazepine high-doses: The need for an accurate definition.

Authors:  Jean-Marc Cloos; Christopher Y S Lim Cow; Valéry Bocquet
Journal:  Int J Methods Psychiatr Res       Date:  2021-07-31       Impact factor: 4.035

  6 in total

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