Literature DB >> 2019534

Myocardial L-carnitine deficiency in a family of dogs with dilated cardiomyopathy.

B W Keene1, D P Panciera, C E Atkins, V Regitz, M J Schmidt, A L Shug.   

Abstract

Dilated cardiomyopathy in a family of dogs was found to be associated with decreased myocardial L-carnitine concentrations, when compared with those in control dogs. In 2 affected dogs, treatment with high doses of L-carnitine was associated with increased myocardial L-carnitine concentration and greatly improved health and myocardial function. Withdrawal of L-carnitine supplementation from these dogs resulted in development of myocardial dysfunction and clinical signs of dilated cardiomyopathy.

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Year:  1991        PMID: 2019534

Source DB:  PubMed          Journal:  J Am Vet Med Assoc        ISSN: 0003-1488            Impact factor:   1.936


  10 in total

Review 1.  Carnitine deficiency-induced cardiomyopathy.

Authors:  D J Paulson
Journal:  Mol Cell Biochem       Date:  1998-03       Impact factor: 3.396

2.  Plasma carnitine levels as a marker of impaired left ventricular functions.

Authors:  W El-Aroussy; A Rizk; G Mayhoub; S A Aleem; S El-Tobgy; M S Mokhtar
Journal:  Mol Cell Biochem       Date:  2000-10       Impact factor: 3.396

Review 3.  Nutrition and cardiomyopathy: lessons from spontaneous animal models.

Authors:  Lisa M Freeman; John E Rush
Journal:  Curr Heart Fail Rep       Date:  2007-06

4.  Characterization of the endogenous carnitine transport and expression of a rat renal Na(+)-dependent carnitine transport system in Xenopus laevis oocytes.

Authors:  S Berardi; B Hagenbuch; E Carafoli; S Krähenbühl
Journal:  Biochem J       Date:  1995-07-15       Impact factor: 3.857

5.  Dilated cardiomyopathy in juvenile Portuguese Water Dogs.

Authors:  Margaret M Sleeper; Paula S Henthorn; C Vijayasarathy; Donna M Dambach; Tim Bowers; Pierre Tijskens; Clara F Armstrong; Edward B Lankford
Journal:  J Vet Intern Med       Date:  2002 Jan-Feb       Impact factor: 3.333

Review 6.  Metabolic Reprogramming, Gut Dysbiosis, and Nutrition Intervention in Canine Heart Disease.

Authors:  Qinghong Li
Journal:  Front Vet Sci       Date:  2022-02-15

7.  Effect of diet change in healthy dogs with subclinical cardiac biomarker or echocardiographic abnormalities.

Authors:  Dana Haimovitz; Michelle Vereb; Lisa Freeman; Robert Goldberg; Darleen Lessard; John Rush; Darcy Adin
Journal:  J Vet Intern Med       Date:  2022-04-14       Impact factor: 3.175

Review 8.  Review of canine dilated cardiomyopathy in the wake of diet-associated concerns.

Authors:  Sydney R McCauley; Stephanie D Clark; Bradley W Quest; Renee M Streeter; Eva M Oxford
Journal:  J Anim Sci       Date:  2020-06-01       Impact factor: 3.159

9.  Investigation of diets associated with dilated cardiomyopathy in dogs using foodomics analysis.

Authors:  Caren E Smith; Laurence D Parnell; Chao-Qiang Lai; John E Rush; Lisa M Freeman
Journal:  Sci Rep       Date:  2021-08-05       Impact factor: 4.379

10.  Acylcarnitine profile in Alaskan sled dogs during submaximal multiday exercise points out metabolic flexibility and liver role in energy metabolism.

Authors:  Irene Tosi; Tatiana Art; François Boemer; Dominique-Marie Votion; Michael S Davis
Journal:  PLoS One       Date:  2021-08-12       Impact factor: 3.240

  10 in total

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