Literature DB >> 20192152

Nonoperative biological treatment approach for partial Achilles tendon lesion.

Giuseppe Filardo1, Mirco Lo Presti, Elizaveta Kon, Maurilio Marcacci.   

Abstract

Tendon injuries, especially those of the Achilles tendon, are major concerns in sports medicine. The clinical presentation can be acute or chronic and the pathologic findings can range from peritendonitis to full-thickness tendon rupture. Nonsurgical treatment is not always successful; in particular, significant partial ruptures seem to respond poorly to conservative measures and do not improve with time. Surgery is most often considered the favored treatment option for this kind of lesion to obtain pain relief and full functionality with long-standing effects.This article describes a case of a partial tear of the Achilles tendon in a 34-year-old competitive athlete where surgical treatment was avoided in favor of a new biological approach. We applied autologous platelet growth factors through multiple platelet-rich plasma injections; approximately 6.5 billion platelets were injected into the lesion 3 times, 7 days apart. The treatment with platelet-rich plasma and a progressive rehabilitation program allowed the patient to play for 20 minutes in a basketball game 64 days after the trauma and in a full game 75 days after the trauma. To date, 18 months later, he has participated regularly in all the season's games and received no further treatment for his tendon.The fast tissue repair, confirmed by magnetic resonance and ultrasound imaging, allowed a swift return to full functionality and competitive sports activity, suggesting a possible role of platelet growth factors in promoting rapid tendon healing with high-quality tissue. This biological approach may represent a less-invasive therapeutic option even in cases where severe tendon lesions are candidates for surgical treatment. Copyright 2010, SLACK Incorporated.

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Year:  2010        PMID: 20192152     DOI: 10.3928/01477447-20100104-31

Source DB:  PubMed          Journal:  Orthopedics        ISSN: 0147-7447            Impact factor:   1.390


  22 in total

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2.  Platelet-rich plasma intra-articular injections for cartilage degeneration and osteoarthritis: single- versus double-spinning approach.

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Review 3.  Platelet-rich plasma (PRP) to treat sports injuries: evidence to support its use.

Authors:  Elizaveta Kon; Giuseppe Filardo; Alessandro Di Martino; Maurilio Marcacci
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4.  Evaluation of autologous platelet concentrate for intertransverse lumbar fusion.

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5.  Quantitative comparison of three rat models of Achilles tendon injury: A multidisciplinary approach.

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6.  Biologics in Achilles tendon healing and repair: a review.

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Review 7.  Platelet-rich plasma: evidence for the treatment of patellar and Achilles tendinopathy--a systematic review.

Authors:  B Di Matteo; G Filardo; E Kon; M Marcacci
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Review 8.  Platelet-rich plasma in tendon-related disorders: results and indications.

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9.  Platelet-rich plasma injections for the treatment of refractory Achilles tendinopathy: results at 4 years.

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Review 10.  Nintendo Wii related Achilles tendon rupture: first reported case and literature review of motion sensing video game injuries.

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