Literature DB >> 20191344

Synthesis and microbiological evaluation of honokiol derivatives as new antimicrobial agents.

Young-Soo Kim1, Ji-Young Lee, Junho Park, Wangtaek Hwang, Jongsung Lee, Deokhoon Park.   

Abstract

Honokiol, a major phenolic constituent of Magnolia sp., has various pharmacological activities. To improve the solubility and antibacterial activity of honokiol against E. coli and P. aeruginosa, new honokiol-derivatives (honokiol-acetate, honokiol-succinic acid, honokiol-glycerol, honokiol-glycine, honokiol-glucose and honokiol-mannose) were synthesized and their solubility and antimicrobial activities were investigated. Among the tested compounds, honokiol-glycine showed improved water solubility and antibacterial activities against E. coli and P. aeruginosa when compared to honokiol.

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Year:  2010        PMID： 20191344     DOI： 10.1007/s12272-010-2225-7

Source DB:  PubMed          Journal:  Arch Pharm Res        ISSN： 0253-6269            Impact factor:   4.946


  11 in total

1.  Chromium-Salen Catalyzed Cross-Coupling of Phenols: Mechanism and Origin of the Selectivity.

Authors:  Yexenia Nieves-Quinones; Thomas J Paniak; Young Eun Lee; Sun Min Kim; Sergei Tcyrulnikov; Marisa C Kozlowski
Journal:  J Am Chem Soc       Date:  2019-06-13       Impact factor: 15.419

2.  Therapeutic Action of Honokiol on Postoperative Ileus via Downregulation of iNOS Gene Expression.

Authors:  Taiki Mihara; Shoma Mikawa; Noriyuki Kaji; Mari Endo; Tetsuro Oikawa; Jan Tong-Rong; Hiroshi Ozaki; Masatoshi Hori
Journal:  Inflammation       Date:  2017-08       Impact factor: 4.092

3.  Honokiol exerts protective effects on neural myelin sheaths after compressed spinal cord injury by inhibiting oligodendrocyte apoptosis through regulation of ER-mitochondrial interactions.

Authors:  Yong Tan; Haijun Yu; Shanquan Sun; Shengwei Gan; Rui Gong; Ke-Jie Mou; Jun Xue; Shiye Xu; Jiangfeng Wu; Lan Ma
Journal:  J Spinal Cord Med       Date:  2021-04-08       Impact factor: 2.040

4.  Antimicrobial Effects and Resistant Regulation of Magnolol and Honokiol on Methicillin-Resistant Staphylococcus aureus.

Authors:  Su Young Kim; Ju Kim; Seung-Il Jeong; Kwang Yeop Jahng; Kang-Yeol Yu
Journal:  Biomed Res Int       Date:  2015-08-19       Impact factor: 3.411

5.  In vitro synergism of magnolol and honokiol in combination with antibacterial agents against clinical isolates of methicillin-resistant Staphylococcus aureus (MRSA).

Authors:  Guo-Ying Zuo; Xin-Juan Zhang; Jun Han; Yu-Qing Li; Gen-Chun Wang
Journal:  BMC Complement Altern Med       Date:  2015-12-01       Impact factor: 3.659

Review 6.  Honokiol and magnolol as multifunctional antioxidative molecules for dermatologic disorders.

Authors:  Jui-Lung Shen; Kee-Ming Man; Po-Hsun Huang; Wen-Chi Chen; Der-Cherng Chen; Ya-Wen Cheng; Po-Len Liu; Ming-Chih Chou; Yung-Hsiang Chen
Journal:  Molecules       Date:  2010-09-16       Impact factor: 4.411

7.  Pharmaceutical Advantages of GenoTX-407, A Combination of Extracts from Scutellaria baicalensis Root and Magnolia officinalis Bark.

Authors:  Eun-Jung Yoon; Mi Young Lee; Byoung Il Choi; Kyong Jin Lim; Seung Young Hong; Dongsun Park
Journal:  Antioxidants (Basel)       Date:  2020-11-11

8.  Syk/Src pathway-targeted inhibition of skin inflammatory responses by carnosic acid.

Authors:  Jueun Oh; Tao Yu; Soo Jeong Choi; Yanyan Yang; Heung Soo Baek; Soon Ae An; Lee Kyoung Kwon; Jinsol Kim; Ho Sik Rho; Song Seok Shin; Wahn Soo Choi; Sungyoul Hong; Jae Youl Cho
Journal:  Mediators Inflamm       Date:  2012-04-10       Impact factor: 4.711

Review 9.  Neuro-modulating effects of honokiol: a review.

Authors:  Anna Woodbury; Shan Ping Yu; Ling Wei; Paul García
Journal:  Front Neurol       Date:  2013-09-11       Impact factor: 4.003

10.  Protective effects of Hericium erinaceus mycelium and its isolated erinacine A against ischemia-injury-induced neuronal cell death via the inhibition of iNOS/p38 MAPK and nitrotyrosine.

Authors:  Kam-Fai Lee; Jiann-Hwa Chen; Chih-Chuan Teng; Chien-Heng Shen; Meng-Chiao Hsieh; Chien-Chang Lu; Ko-Chao Lee; Li-Ya Lee; Wan-Ping Chen; Chin-Chu Chen; Wen-Shih Huang; Hsing-Chun Kuo
Journal:  Int J Mol Sci       Date:  2014-08-27       Impact factor: 5.923
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