Literature DB >> 20190102

Composite tissue allotransplantation: hand transplantation and beyond.

Jaimie T Shores1, Gerald Brandacher, Stefan Schneeberger, Vijay S Gorantla, W P Andrew Lee.   

Abstract

Recent advances in transplant immunology are shifting the focus from immunosuppression to immunoregulation, making composite tissue allotransplantation with novel and less potent immunosuppressive regimens a possibility. Hand transplantation has been the most frequently performed human composite tissue allotransplantation, with more than 50 upper extremity-based transplants done worldwide. Further research is needed regarding immunomodulating protocols, and careful oversight and individualized screening procedures will be required as patients seeking improved quality of life through human composite tissue allotransplantation come to accept a certain level of risk in these experimental procedures. Still, composite tissue allotransplantation offers to advance transplant medicine and reconstructive surgery.

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Year:  2010        PMID： 20190102     DOI： 10.5435/00124635-201003000-00001

Source DB:  PubMed          Journal:  J Am Acad Orthop Surg        ISSN： 1067-151X            Impact factor:   3.020


  8 in total

Review 1.  Technology and vascularized composite allotransplantation (VCA)-lessons learned from the first bilateral pediatric hand transplant.

Authors:  Arash Momeni; Benjamin Chang; L Scott Levin
Journal:  J Mater Sci Mater Med       Date:  2016-09-16       Impact factor: 3.896

Review 2.  Key psychosocial challenges in vascularized composite allotransplantation.

Authors:  Martin Kumnig; Sheila G Jowsey-Gregoire
Journal:  World J Transplant       Date:  2016-03-24

Review 3.  Surgical, ethical, and psychosocial considerations in human head transplantation.

Authors:  Allen Furr; Mark A Hardy; Juan P Barret; John H Barker
Journal:  Int J Surg       Date:  2017-01-19       Impact factor: 6.071

4.  Neural activation for actual and imagined movement following unilateral hand transplantation: a case study.

Authors:  David J Madden; M Stephen Melton; Shivangi Jain; Angela D Cook; Jeffrey N Browndyke; Todd B Harshbarger; Linda C Cendales
Journal:  Neurocase       Date:  2019-09-24       Impact factor: 0.881

5.  History and ethics of hand transplants.

Authors:  Michael Errico; Neil H Metcalfe; Alastair Platt
Journal:  JRSM Short Rep       Date:  2012-10-26

6.  Effects of electrical stimulation on rat limb regeneration, a new look at an old model.

Authors:  Liudmila P Leppik; Dara Froemel; Andrei Slavici; Zachri N Ovadia; Lukasz Hudak; Dirk Henrich; Ingo Marzi; John H Barker
Journal:  Sci Rep       Date:  2015-12-17       Impact factor: 4.379

7.  The role of imaging in patient selection, preoperative planning, and postoperative monitoring in human upper extremity allotransplantation.

Authors:  Eira S Roth; David G Buck; Vijay S Gorantla; Joseph E Losee; Daniel E Foust; Cynthia A Britton
Journal:  J Transplant       Date:  2014-03-27

8.  Evolving ethics, policy and reimbursement issues of vascularized composite allotransplantation: Symposium summary.

Authors:  John Rose; Carisa M Cooney; Christina Kaufman; Simon G Talbot; Arthur Caplan; Jeffrey Kahn; Jeremy Sugarman; Jaimie T Shores; L Scott Levin; Gerald Brandacher; Sue V McDiarmid; Wp Andrew Lee; Wendy Dean
Journal:  SAGE Open Med       Date:  2019-07-26
  8 in total

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