Literature DB >> 20184967

Delivery of anti-angiogenic molecular therapies for retinal disease.

Owen A Anderson1, James W B Bainbridge, David T Shima.   

Abstract

Angiogenic diseases of the retina are the leading cause of blindness in the developed world. The development of anti-angiogenic molecular therapies has transformed the prognosis of these conditions, especially age-related macular degeneration. With these new treatments comes the new challenge of delivering an effective dosage to the retina, over a prolonged period of time and in a safe and cost-effective manner. A range of new anti-angiogenics are on the horizon, offering new and varied modes of drug delivery. In addition, a range of new sustained-release drug delivery technologies are being developed. 2010 Elsevier Ltd. All rights reserved.

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Year:  2010        PMID： 20184967     DOI： 10.1016/j.drudis.2010.02.004

Source DB:  PubMed          Journal:  Drug Discov Today        ISSN： 1359-6446            Impact factor:   7.851


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