| Literature DB >> 20184316 |
K C Nicolaou1, Hanfeng Ding, Jean-Alexandre Richard, David Y-K Chen.
Abstract
Echinopines A and B [(+)-1 and (+)-2], two naturally occurring compounds characterized with a unique [3.5.5.7] carbon framework, have been synthesized in both enantiomeric and racemic forms. Their total synthesis involves a novel intramolecular rhodium-catalyzed cyclopropanation (4 --> 16) and a samarium diiodide-mediated ring closure (3 --> 37).Entities:
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Year: 2010 PMID： 20184316 DOI： 10.1021/ja9093988
Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419