Literature DB >> 20184026

4'-O-methylglycosylation of curcumin by Beauveria bassiana.

Jia Zeng1, Nan Yang, Xiu-Min Li, Paul J Shami, Jixun Zhan.   

Abstract

The applications of curcumin have been limited by its poor water solubility and low bioavailability. In this study, we successfully synthesized a new curcumin derivative, curcumin-8'-O-4"-O-methyl-beta-D-glucopyranoside, by biotransformation with the fungal strain Beauveria bassiana ATCC 7159. The structure of this new product was determined on the basis of spectroscopic data. This is the first record of a curcumin glycoside that has been synthesized by a fungus.

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Year:  2010        PMID： 20184026

Source DB:  PubMed          Journal:  Nat Prod Commun        ISSN： 1555-9475            Impact factor:   0.986


  2 in total

1.  Methylglucosylation of aromatic amino and phenolic moieties of drug-like biosynthons by combinatorial biosynthesis.

Authors:  Linan Xie; Liwen Zhang; Chen Wang; Xiaojing Wang; Ya-Ming Xu; Hefen Yu; Ping Wu; Shenglan Li; Lida Han; A A Leslie Gunatilaka; Xiaoyi Wei; Min Lin; István Molnár; Yuquan Xu
Journal:  Proc Natl Acad Sci U S A       Date:  2018-05-14       Impact factor: 11.205

2.  A highly versatile fungal glucosyltransferase for specific production of quercetin-7-O-β-D-glucoside and quercetin-3-O-β-D-glucoside in different hosts.

Authors:  Jie Ren; Wenzhu Tang; Caleb Don Barton; Owen M Price; Mark Wayne Mortensen; Alexandra Phillips; Banner Wald; Simon Elgin Hulme; Logan Powell Stanley; Joan Hevel; Jixun Zhan
Journal:  Appl Microbiol Biotechnol       Date:  2021-12-07       Impact factor: 4.813
  2 in total

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