Literature DB >> 20184014

New anti-inflammatory sterols from the Red Sea sponges Scalarispongia aqabaensis and Callyspongia siphonella.

Diaa T A Youssef1, Amany K Ibrahim, Sherief I Khalifa, Mostafa K Mesbah, Alejandro M S Mayer, Rob W M van Soest.   

Abstract

Bioassay-guided fractionation of the anti-inflammation fractions of the Red Sea sponges Scalarispongia aqabaensis and Callyspongia siphonella yielded two new sterols from chloroform fractions of methanol extracts, namely scalaristerol (5alpha,8alpha-dihydroxycholest-6-en-3beta-ol) (1) from Scalarispongia aqabaensis, and callysterol (ergosta-5,11-dien-3beta-ol) (2) from Callyspongia siphonella. Structure determination was based on extensive NMR studies and mass spectrometry. The antiinflammatory activity of compounds 1 and 2 was assessed using the rat-hind paw edema method and by study of their effect on the release of O2(-) and TXB2 from LPS-activated rat neonatal microglia.

Entities:  

Mesh：

Substances：

Year:  2010        PMID： 20184014

Source DB:  PubMed          Journal:  Nat Prod Commun        ISSN： 1555-9475            Impact factor:   0.986


  10 in total

1.  New cytotoxic polyacetylene alcohols from the Egyptian marine sponge Siphonochalina siphonella.

Authors:  Dae-Won Ki; Ahmed H El-Desoky; Chin Piow Wong; Mohamed Abdel-Ghani; Ahmed A El-Beih; Mineyuki Mizuguchi; Hiroyuki Morita
Journal:  J Nat Med       Date:  2019-12-13       Impact factor: 2.343

2.  Evaluation of the Anti-Inflammatory, Antioxidant and Immunomodulatory Effects of the Organic Extract of the Red Sea Marine Sponge Xestospongia testudinaria against Carrageenan Induced Rat Paw Inflammation.

Authors:  Nagla A El-Shitany; Lamiaa A Shaala; Aymn T Abbas; Umama A Abdel-Dayem; Esam I Azhar; Soad S Ali; Rob W M van Soest; Diaa T A Youssef
Journal:  PLoS One       Date:  2015-09-30       Impact factor: 3.240

Review 3.  Marine pharmacology in 2009-2011: marine compounds with antibacterial, antidiabetic, antifungal, anti-inflammatory, antiprotozoal, antituberculosis, and antiviral activities; affecting the immune and nervous systems, and other miscellaneous mechanisms of action.

Authors:  Alejandro M S Mayer; Abimael D Rodríguez; Orazio Taglialatela-Scafati; Nobuhiro Fusetani
Journal:  Mar Drugs       Date:  2013-07-16       Impact factor: 5.118

4.  Cytotoxic Metabolites from Callyspongia siphonella Display Antiproliferative Activity by Inducing Apoptosis in HCT-116 Cells.

Authors:  Tariq R A Sobahi; Seif-Eldin N Ayyad; Ahmed Abdel-Lateff; Mardi M Algandaby; Hajer S Alorfi; Ashraf B Abdel-Naim
Journal:  Pharmacogn Mag       Date:  2017-04-07       Impact factor: 1.085

5.  Bioactive Brominated Oxindole Alkaloids from the Red Sea Sponge Callyspongia siphonella.

Authors:  Seham S El-Hawary; Ahmed M Sayed; Rabab Mohammed; Hossam M Hassan; Mostafa E Rateb; Elham Amin; Tarek A Mohammed; Mohamed El-Mesery; Abdullatif Bin Muhsinah; Abdulrhman Alsayari; Harald Wajant; Mohamed A Anany; Usama Ramadan Abdelmohsen
Journal:  Mar Drugs       Date:  2019-08-09       Impact factor: 5.118

Review 6.  Marine Ligands of the Pregnane X Receptor (PXR): An Overview.

Authors:  Alejandro Carazo; Přemysl Mladěnka; Petr Pávek
Journal:  Mar Drugs       Date:  2019-09-28       Impact factor: 5.118

7.  Antimicrobial Chlorinated 3-Phenylpropanoic Acid Derivatives from the Red Sea Marine Actinomycete Streptomyces coelicolor LY001.

Authors:  Lamiaa A Shaala; Diaa T A Youssef; Torki A Alzughaibi; Sameh S Elhady
Journal:  Mar Drugs       Date:  2020-08-27       Impact factor: 5.118

8.  Roots of Erigeron annuus Attenuate Acute Inflammation as Mediated with the Inhibition of NF- κ B-Associated Nitric Oxide and Prostaglandin E2 production.

Authors:  Mi Jeong Jo; Jong Rok Lee; Il Je Cho; Young Woo Kim; Sang Chan Kim
Journal:  Evid Based Complement Alternat Med       Date:  2013-02-24       Impact factor: 2.629

Review 9.  Collective Locomotion of Human Cells, Wound Healing and Their Control by Extracts and Isolated Compounds from Marine Invertebrates.

Authors:  Claudio Luparello; Manuela Mauro; Valentina Lazzara; Mirella Vazzana
Journal:  Molecules       Date:  2020-05-26       Impact factor: 4.411

Review 10.  Metabolities from Marine Sponges of the Genus Callyspongia: Occurrence, Biological Activity, and NMR Data.

Authors:  Lucas Hilário Nogueira de Sousa; Rusceli Diego de Araújo; Déborah Sousa-Fontoura; Fabrício Gava Menezes; Renata Mendonça Araújo
Journal:  Mar Drugs       Date:  2021-11-26       Impact factor: 5.118
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.