Literature DB >> 20183332

Two new cytotoxic cardenolides from the latex of Antiaris toxicaria.

Hao-Fu Dai1, Yu-Juan Gan, Dong-Mei Que, Jiao Wu, Zhen-Chang Wen, Wen-Li Mei.   

Abstract

Two new cardenolides, toxicarioside F (1) and toxicarioside G (2), were isolated from the latex of Antiaris toxicaria (Pers.) Lesch (Moraceae). Their structures were elucidated on the basis of spectral data and chemical evidence. Compounds 1 and 2 showed significant cytotoxicity against K562, SGC-7901, SMMC-7721, and HeLa cell lines in vitro by the MTT method.

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Year:  2009        PMID： 20183332     DOI： 10.1080/10286020903164285

Source DB:  PubMed          Journal:  J Asian Nat Prod Res        ISSN： 1028-6020            Impact factor:   1.569


  7 in total

1.  Toxicarioside A inhibits SGC-7901 proliferation, migration and invasion via NF-κB/bFGF signaling.

Authors:  Jun-Li Guo; Shao-Jiang Zheng; Yue-Nan Li; Wei Jie; Xin-Bao Hao; Tian-Fa Li; Li-Ping Xia; Wen-Li Mei; Feng-Ying Huang; Yue-Qiong Kong; Qi-Yi He; Kun Yang; Guang-Hong Tan; Hao-Fu Dai
Journal:  World J Gastroenterol       Date:  2012-04-14       Impact factor: 5.742

2.  Cytotoxic cardiac glycosides and coumarins from Antiaris toxicaria.

Authors:  Li-Shian Shi; Sheng-Chu Kuo; Han-Dong Sun; Susan L Morris-Natschke; Kuo-Hsiung Lee; Tian-Shung Wu
Journal:  Bioorg Med Chem       Date:  2014-02-06       Impact factor: 3.641

3.  Strophalloside induces apoptosis of SGC-7901 cells through the mitochondrion-dependent caspase-3 pathway.

Authors:  Xue-Jiao Zhang; Wen-Li Mei; Guang-Hong Tan; Cai-Chun Wang; Song-Lin Zhou; Feng-Ru Huang; Bin Chen; Hao-Fu Dai; Feng-Ying Huang
Journal:  Molecules       Date:  2015-03-31       Impact factor: 4.411

4.  YAP activation attenuates toxicarioside G‑induced lethal autophagy arrest in SW480 colorectal cancer cells.

Authors:  Limin Zhou; Jinyan Wang; Jiaqi Liu; Jiantang Liang; Yansong Wang; Qunfang Cai; Yonghao Huang
Journal:  Oncol Rep       Date:  2021-08-30       Impact factor: 3.906

5.  Toxicarioside A inhibits tumor growth and angiogenesis: involvement of TGF-β/endoglin signaling.

Authors:  Feng-Ying Huang; Wen-Li Mei; Yue-Nan Li; Guang-Hong Tan; Hao-Fu Dai; Jun-Li Guo; Hua Wang; Yong-Hao Huang; Huan-Ge Zhao; Song-Lin Zhou; Ying-Ying Lin
Journal:  PLoS One       Date:  2012-11-28       Impact factor: 3.240

6.  Toxicarioside O induces protective autophagy in a sirtuin-1-dependent manner in colorectal cancer cells.

Authors:  Yong-Hao Huang; Yan Sun; Feng-Ying Huang; Yue-Nan Li; Cai-Chun Wang; Wen-Li Mei; Hao-Fu Dai; Guang-Hong Tan; Canhua Huang
Journal:  Oncotarget       Date:  2017-04-18

7.  A new cytotoxic 19-nor-cardenolide from the latex of Antiaris toxicaria.

Authors:  Hao-Fu Dai; Yu-Juan Gan; Dong-Mei Que; Jiao Wu; Zhen-Chang Wen; Wen-Li Mei
Journal:  Molecules       Date:  2009-09-21       Impact factor: 4.411
  7 in total

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