Literature DB >> 20182820

Inflammatory biomarkers and coronary heart disease: from bench to bedside and back.

Gina Biasillo1, Milena Leo, Roberta Della Bona, Luigi Marzio Biasucci.   

Abstract

Inflammation plays a pivotal role in all stages of atherosclerosis from endothelial dysfunction and plaque formation to plaque destabilization and disruption. Inflammatory biomarkers, originally studied to better understand the pathophysiology of atherosclerosis, have generated increasing interest among clinicians, because of their utility in the challenging problems of diagnosis and risk assessment of patients with suspected or proved coronary heart disease. Moreover, in fascinating perspective, they could be used as therapeutic target, counteracting initiation, progression, and development of complications of atherosclerosis. In this review, we will provide an overview of the more promising inflammatory biomarkers, focusing on their utility and limitations in the clinical setting.

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Year:  2010        PMID: 20182820     DOI: 10.1007/s11739-010-0361-1

Source DB:  PubMed          Journal:  Intern Emerg Med        ISSN: 1828-0447            Impact factor:   3.397


  49 in total

1.  Production of C-reactive protein and risk of coronary events in stable and unstable angina. European Concerted Action on Thrombosis and Disabilities Angina Pectoris Study Group.

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Journal:  Lancet       Date:  1997-02-15       Impact factor: 79.321

2.  Predictive value of C-reactive protein and troponin T in patients with unstable angina: a comparative analysis. CAPTURE Investigators. Chimeric c7E3 AntiPlatelet Therapy in Unstable angina REfractory to standard treatment trial.

Authors:  C Heeschen; C W Hamm; J Bruemmer; M L Simoons
Journal:  J Am Coll Cardiol       Date:  2000-05       Impact factor: 24.094

3.  Targeting C-reactive protein for the treatment of cardiovascular disease.

Authors:  Mark B Pepys; Gideon M Hirschfield; Glenys A Tennent; J Ruth Gallimore; Melvyn C Kahan; Vittorio Bellotti; Philip N Hawkins; Rebecca M Myers; Martin D Smith; Alessandra Polara; Alexander J A Cobb; Steven V Ley; J Andrew Aquilina; Carol V Robinson; Isam Sharif; Gillian A Gray; Caroline A Sabin; Michelle C Jenvey; Simon E Kolstoe; Darren Thompson; Stephen P Wood
Journal:  Nature       Date:  2006-04-27       Impact factor: 49.962

4.  Relationship between interleukin 6 and mortality in patients with unstable coronary artery disease: effects of an early invasive or noninvasive strategy.

Authors:  E Lindmark; E Diderholm; L Wallentin; A Siegbahn
Journal:  JAMA       Date:  2001-11-07       Impact factor: 56.272

5.  Preprocedural serum levels of C-reactive protein predict early complications and late restenosis after coronary angioplasty.

Authors:  A Buffon; G Liuzzo; L M Biasucci; P Pasqualetti; V Ramazzotti; A G Rebuzzi; F Crea; A Maseri
Journal:  J Am Coll Cardiol       Date:  1999-11-01       Impact factor: 24.094

6.  Elevated levels of C-reactive protein at discharge in patients with unstable angina predict recurrent instability.

Authors:  L M Biasucci; G Liuzzo; R L Grillo; G Caligiuri; A G Rebuzzi; A Buffon; F Summaria; F Ginnetti; G Fadda; A Maseri
Journal:  Circulation       Date:  1999-02-23       Impact factor: 29.690

7.  Circulating pregnancy-associated plasma protein A is not an early marker of acute myocardial infarction.

Authors:  Alberto Dominguez-Rodriguez; Pedro Abreu-Gonzalez; Martín Garcia-Gonzalez; Julio Ferrer; Manuel Vargas
Journal:  Clin Biochem       Date:  2005-02       Impact factor: 3.281

8.  Soluble CD40 ligand in acute coronary syndromes.

Authors:  Christopher Heeschen; Stefanie Dimmeler; Christian W Hamm; Marcel J van den Brand; Eric Boersma; Andreas M Zeiher; Maarten L Simoons
Journal:  N Engl J Med       Date:  2003-03-20       Impact factor: 91.245

9.  Concurrent evaluation of novel cardiac biomarkers in acute coronary syndrome: myeloperoxidase and soluble CD40 ligand and the risk of recurrent ischaemic events in TACTICS-TIMI 18.

Authors:  David A Morrow; Marc S Sabatine; Marie-Luise Brennan; James A de Lemos; Sabina A Murphy; Christian T Ruff; Nader Rifai; Christopher P Cannon; Stanley L Hazen
Journal:  Eur Heart J       Date:  2008-03-12       Impact factor: 29.983

10.  Serum myeloperoxidase levels are associated with the future risk of coronary artery disease in apparently healthy individuals: the EPIC-Norfolk Prospective Population Study.

Authors:  Marijn C Meuwese; Erik S G Stroes; Stanley L Hazen; Joram N van Miert; Jan Albert Kuivenhoven; Robert G Schaub; Nicholas J Wareham; Robert Luben; John J P Kastelein; Kay-Tee Khaw; S Matthijs Boekholdt
Journal:  J Am Coll Cardiol       Date:  2007-06-21       Impact factor: 24.094

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  19 in total

1.  Pretreatment with quercetin prevents changes in lymphocytes E-NTPDase/E-ADA activities and cytokines secretion in hyperlipidemic rats.

Authors:  Josiane B S Braun; Jader B Ruchel; Alessandra G Manzoni; Fátima H Abdalla; Emerson A Casalli; Lívia G Castilhos; Daniela F Passos; Daniela B R Leal
Journal:  Mol Cell Biochem       Date:  2017-11-29       Impact factor: 3.396

Review 2.  Clinical utility of novel biomarkers for cardiovascular disease risk stratification.

Authors:  Maurizio Averna; Davide Noto
Journal:  Intern Emerg Med       Date:  2012-10       Impact factor: 3.397

Review 3.  Risk of venous thromboembolism in patients with idiopathic inflammatory myositis: a systematic review and meta-analysis.

Authors:  Patompong Ungprasert; Anawin Sanguankeo
Journal:  Rheumatol Int       Date:  2014-04-20       Impact factor: 2.631

4.  Pro-inflammatory genetic profile and familiarity of acute myocardial infarction.

Authors:  Manuela Ianni; Sergio Callegari; Antonio Rizzo; Paolo Pastori; Paolo Moruzzi; Domenico Corradi; Elisa Porcellini; Gianluca Campo; Roberto Ferrari; Marco M Ferrario; Stefania Bitonte; Ilaria Carbone; Federico Licastro
Journal:  Immun Ageing       Date:  2012-06-24       Impact factor: 6.400

5.  CRP and TNF-α  induce PAPP-A expression in human peripheral blood mononuclear cells.

Authors:  Weiping Li; Hongwei Li; Fusheng Gu
Journal:  Mediators Inflamm       Date:  2012-09-11       Impact factor: 4.711

6.  Neovascularization of coronary tunica intima (DIT) is the cause of coronary atherosclerosis. Lipoproteins invade coronary intima via neovascularization from adventitial vasa vasorum, but not from the arterial lumen: a hypothesis.

Authors:  Vladimir M Subbotin
Journal:  Theor Biol Med Model       Date:  2012-04-10       Impact factor: 2.432

7.  Left ventricular mass in dialysis patients, determinants and relation with outcome. Results from the COnvective TRansport STudy (CONTRAST).

Authors:  Ira M Mostovaya; Michiel L Bots; Marinus A van den Dorpel; Roel Goldschmeding; Claire H den Hoedt; Otto Kamp; Renée Levesque; Albert H A Mazairac; E Lars Penne; Dorine W Swinkels; Neelke C van der Weerd; Piet M Ter Wee; Menso J Nubé; Peter J Blankestijn; Muriel P C Grooteman
Journal:  PLoS One       Date:  2014-02-05       Impact factor: 3.240

8.  Dynamic reorganization of the AC16 cardiomyocyte transcriptome in response to TNFα signaling revealed by integrated genomic analyses.

Authors:  Xin Luo; Minho Chae; Raga Krishnakumar; Charles G Danko; W Lee Kraus
Journal:  BMC Genomics       Date:  2014-02-24       Impact factor: 3.969

9.  Overexpression of YKL-40 predicts plaque instability in carotid atherosclerosis with CagA-positive Helicobacter pylori infection.

Authors:  Yina Wu; Zhen Tao; Chao Song; Qingshuai Jia; Jun Bai; Kangkang Zhi; Lefeng Qu
Journal:  PLoS One       Date:  2013-04-03       Impact factor: 3.240

10.  Pregnancy-associated plasma protein A predicts adverse vascular events in patients with coronary heart disease: a systematic review and meta-analysis.

Authors:  Yuehua Li; Chenghui Zhou; Xianliang Zhou; Lihuan Li; Rutai Hui
Journal:  Arch Med Sci       Date:  2013-05-28       Impact factor: 3.318

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