| Literature DB >> 20181399 |
Binbin Wang1, Shiyi Zhou, Qiuhong Chen, XiaoDong Xie, Guoying Huang, Jing Wang, Sirui Zhoua, Xu Ma.
Abstract
Congenital heart disease (CHD) is the malformation of the heart during embryonic development, contributing to the inadequate function of the heart. A recently suggested gene hairy-related transcription factor 2 (HEY2), is an important determinant of mammalian heart development and functions thereby. We had preformed a direct sequencing within 768 Chinese CHD patients in the HEY2 gene. However, we did not reveal any diagnostic alterations in the coding regions by direct sequencing in HEY2, nevertheless this work expands our knowledge of the causes of CHD in the other way.Entities:
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Year: 2010 PMID： 20181399 DOI： 10.1016/j.ijcard.2009.12.013
Source DB: PubMed Journal: Int J Cardiol ISSN： 0167-5273 Impact factor: 4.164