PURPOSE OF REVIEW: To assess the current status and technological advances in image-guided external beam radiotherapy for prostate cancer. RECENT FINDINGS: Modern imaging has improved the ability to define radiotherapy target volumes. Specifically, treatment margins have been reduced through the use of treatment planning and image-guidance technology. Increasing dose has led to increased disease control. Concurrent technological advances may improve treatment-related toxicity. Data continues to emerge on patient selection, treatment schedule, and use of additional systemic therapy in conjunction with radiation. SUMMARY: In the present article, we review recent developments in radiation planning, image guidance, patient selection and fractionation, dose escalation, toxicity, systemic therapy, and follow-up.
PURPOSE OF REVIEW: To assess the current status and technological advances in image-guided external beam radiotherapy for prostate cancer. RECENT FINDINGS: Modern imaging has improved the ability to define radiotherapy target volumes. Specifically, treatment margins have been reduced through the use of treatment planning and image-guidance technology. Increasing dose has led to increased disease control. Concurrent technological advances may improve treatment-related toxicity. Data continues to emerge on patient selection, treatment schedule, and use of additional systemic therapy in conjunction with radiation. SUMMARY: In the present article, we review recent developments in radiation planning, image guidance, patient selection and fractionation, dose escalation, toxicity, systemic therapy, and follow-up.
Authors: Nicholas G Zaorsky; Amy S Harrison; Edouard J Trabulsi; Leonard G Gomella; Timothy N Showalter; Mark D Hurwitz; Adam P Dicker; Robert B Den Journal: Nat Rev Urol Date: 2013-09-10 Impact factor: 14.432
Authors: Nicholas G Zaorsky; Timothy N Showalter; Gary A Ezzell; Paul L Nguyen; Dean G Assimos; Anthony V D'Amico; Alexander R Gottschalk; Gary S Gustafson; Sameer R Keole; Stanley L Liauw; Shane Lloyd; Patrick W McLaughlin; Benjamin Movsas; Bradley R Prestidge; Al V Taira; Neha Vapiwala; Brian J Davis Journal: Adv Radiat Oncol Date: 2016-10-20
Authors: Nicholas G Zaorsky; Timothy N Showalter; Gary A Ezzell; Paul L Nguyen; Dean G Assimos; Anthony V D'Amico; Alexander R Gottschalk; Gary S Gustafson; Sameer R Keole; Stanley L Liauw; Shane Lloyd; Patrick W McLaughlin; Benjamin Movsas; Bradley R Prestidge; Al V Taira; Neha Vapiwala; Brian J Davis Journal: Adv Radiat Oncol Date: 2017-03-20