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Literature DB >> 20178857

Targeting effectors: the molecular recognition of Type III secreted proteins.

Roland Arnold¹, Andre Jehl, Thomas Rattei.

Abstract

The Type III secretion system (TTSS) facilitates the export of effector proteins from pathogenic and symbiotic Gram-negative bacteria into the cytosol of eukaryotic host cells. The current functional and evolutionary knowledge on the molecular recognition of TTSS substrates and computational models of the secretion signal are discussed in this review. Copyright 2010 Elsevier Masson SAS. All rights reserved.

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Year: 2010 PMID： 20178857 DOI： 10.1016/j.micinf.2010.02.003

Source DB: PubMed Journal: Microbes Infect ISSN： 1286-4579 Impact factor: 2.700

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Cited

15 in total

1. TRIF mobilizes unique primary defense against Gram-negative bacteria in intestinal interface.

Authors: John Sotolongo; Saravana Kanagavelu; Jinhee Hyun; Jose Ruiz; Masayuki Fukata
Journal: Gut Microbes Date: 2012-06-20

2. Structural and functional analysis of the type III secretion system from Pseudomonas fluorescens Q8r1-96.

Authors: Dmitri V Mavrodi; Anna Joe; Olga V Mavrodi; Karl A Hassan; David M Weller; Ian T Paulsen; Joyce E Loper; James R Alfano; Linda S Thomashow
Journal: J Bacteriol Date: 2010-10-22 Impact factor: 3.490

3. Assignment of function to a domain of unknown function: DUF1537 is a new kinase family in catabolic pathways for acid sugars.

Authors: Xinshuai Zhang; Michael S Carter; Matthew W Vetting; Brian San Francisco; Suwen Zhao; Nawar F Al-Obaidi; Jose O Solbiati; Jennifer J Thiaville; Valérie de Crécy-Lagard; Matthew P Jacobson; Steven C Almo; John A Gerlt
Journal: Proc Natl Acad Sci U S A Date: 2016-07-11 Impact factor: 11.205

Targeting effectors: the molecular recognition of Type III secreted proteins.

1. TRIF mobilizes unique primary defense against Gram-negative bacteria in intestinal interface.

2. Structural and functional analysis of the type III secretion system from Pseudomonas fluorescens Q8r1-96.

3. Assignment of function to a domain of unknown function: DUF1537 is a new kinase family in catabolic pathways for acid sugars.

4. The role of innate immunity in the host defense against intestinal bacterial pathogens.

Review 5. Vibrio parahaemolyticus cell biology and pathogenicity determinants.

Review 6. Bacterial type III secretion systems: specialized nanomachines for protein delivery into target cells.

7. Effective identification of bacterial type III secretion signals using joint element features.

8. HrcQ provides a docking site for early and late type III secretion substrates from Xanthomonas.

9. T3_MM: a Markov model effectively classifies bacterial type III secretion signals.

10. Engineering the type III secretion system in non-replicating bacterial minicells for antigen delivery.