Literature DB >> 20178740

Lymphangiogenesis: Molecular mechanisms and future promise.

Tuomas Tammela1, Kari Alitalo.   

Abstract

The growth of lymphatic vessels (lymphangiogenesis) is actively involved in a number of pathological processes including tissue inflammation and tumor dissemination but is insufficient in patients suffering from lymphedema, a debilitating condition characterized by chronic tissue edema and impaired immunity. The recent explosion of knowledge on the molecular mechanisms governing lymphangiogenesis provides new possibilities to treat these diseases. 2010 Elsevier Inc. All rights reserved.

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Year:  2010        PMID: 20178740     DOI: 10.1016/j.cell.2010.01.045

Source DB:  PubMed          Journal:  Cell        ISSN: 0092-8674            Impact factor:   41.582


  538 in total

1.  Lymphatic microvessel density as a prognostic factor in non-small cell lung carcinoma: a meta-analysis of the literature.

Authors:  Jun Wang; Kainan Li; Baocheng Wang; Jingwang Bi
Journal:  Mol Biol Rep       Date:  2011-12-14       Impact factor: 2.316

2.  Stromal expression of vascular endothelial growth factor C is relevant to predict sentinel lymph node status in melanomas.

Authors:  Elena Gallego; Luis Vicioso; Martina Alvarez; Isabel Hierro; Lidia Pérez-Villa; Alfredo Blanes; Alfredo Matilla
Journal:  Virchows Arch       Date:  2011-01-29       Impact factor: 4.064

3.  Connexin37 and Connexin43 deficiencies in mice disrupt lymphatic valve development and result in lymphatic disorders including lymphedema and chylothorax.

Authors:  John D Kanady; Michael T Dellinger; Stephanie J Munger; Marlys H Witte; Alexander M Simon
Journal:  Dev Biol       Date:  2011-04-16       Impact factor: 3.582

4.  ETS transcription factor Etsrp / Etv2 is required for lymphangiogenesis and directly regulates vegfr3 / flt4 expression.

Authors:  Jennifer A Davis; Andrew L Koenig; Allison Lubert; Brendan Chestnut; Fang Liu; Sharina Palencia Desai; Tamara Winkler; Karolina Pociute; Kyunghee Choi; Saulius Sumanas
Journal:  Dev Biol       Date:  2018-05-09       Impact factor: 3.582

Review 5.  Endothelial Metabolic Control of Lymphangiogenesis.

Authors:  Pengchun Yu; Guosheng Wu; Heon-Woo Lee; Michael Simons
Journal:  Bioessays       Date:  2018-05-11       Impact factor: 4.345

6.  Non-invasive dynamic near-infrared imaging and quantification of vascular leakage in vivo.

Authors:  Steven T Proulx; Paola Luciani; Annamari Alitalo; Viviane Mumprecht; Ailsa J Christiansen; Reto Huggenberger; Jean-Christophe Leroux; Michael Detmar
Journal:  Angiogenesis       Date:  2013-01-17       Impact factor: 9.596

Review 7.  Beyond a Passive Conduit: Implications of Lymphatic Biology for Kidney Diseases.

Authors:  Daniyal J Jafree; David A Long
Journal:  J Am Soc Nephrol       Date:  2020-04-15       Impact factor: 10.121

8.  Divergence of zebrafish and mouse lymphatic cell fate specification pathways.

Authors:  Andreas van Impel; Zhonghua Zhao; Dorien M A Hermkens; M Guy Roukens; Johanna C Fischer; Josi Peterson-Maduro; Henricus Duckers; Elke A Ober; Philip W Ingham; Stefan Schulte-Merker
Journal:  Development       Date:  2014-02-12       Impact factor: 6.868

9.  Adrenomedullin gene dosage correlates with tumor and lymph node lymphangiogenesis.

Authors:  Natalie O Karpinich; Daniel O Kechele; Scott T Espenschied; Helen H Willcockson; Yuri Fedoriw; Kathleen M Caron
Journal:  FASEB J       Date:  2012-10-25       Impact factor: 5.191

10.  Lymphovascular invasion in breast cancer is associated with gene expression signatures of cell proliferation but not lymphangiogenesis or immune response.

Authors:  Mariko Asaoka; Santosh K Patnaik; Frank Zhang; Takashi Ishikawa; Kazuaki Takabe
Journal:  Breast Cancer Res Treat       Date:  2020-04-13       Impact factor: 4.872

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