Literature DB >> 20178006

Paget's disease of the cervical spine: case report and review.

B Lenehan1, J Street, N Cassidy.   

Abstract

STUDY
DESIGN: This article presents a case of Paget's disease of the cervical spine.
OBJECTIVES: To report a very rare case of Paget's disease of the cervical spine and review the literature.
METHODS: We report a case of Paget's disease of the cervical spine in a 51-year-old male presenting with neck pain post RTA. Routine radiographs revealed enlarged sclerotic bodies of C2-C5 with normal alignment. CT revealed a fracture of the lateral mass of C2 with extensive sclerotic changes in the bodies of C2-C5 with periosteal apposition, endosteal resorption "pumice stone" type focal periosteal apposition consistent with Paget's disease. Laboratory investigations were consistent with a diagnosis of Paget's disease. Isotope bone scan revealed isolated uptake in the cervical spine. He was commenced on biosphosphonate therapy. Following 12 weeks of immobilisation his orthosis was removed and rehabilitation commenced.
RESULTS: At 12-month follow-up he is asymptomatic with no radiological change.
CONCLUSION: This case illustrates the investigation and successful management of a very rare case of Paget's disease of the cervical spine.

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Year:  2010        PMID: 20178006      PMCID: PMC7103221          DOI: 10.1007/s11845-010-0463-9

Source DB:  PubMed          Journal:  Ir J Med Sci        ISSN: 0021-1265            Impact factor:   1.568


  12 in total

1.  Paget's disease of the axis causing quadriplegia.

Authors:  B RAMAMURTHI; G S VISVANATHAN
Journal:  J Neurosurg       Date:  1957-09       Impact factor: 5.115

2.  Paget's disease of bone; incidence and subclinical forms.

Authors:  D H COLLINS
Journal:  Lancet       Date:  1956-07-14       Impact factor: 79.321

3.  Spinal cord compression secondary to Paget's disease of the axis.

Authors:  R Mawhinney; R Jones; B S Worthington
Journal:  Br J Radiol       Date:  1985-12       Impact factor: 3.039

4.  Paget's disease of the atlas and axis.

Authors:  H P Brown; H LaRocca; J K Wickstrom
Journal:  J Bone Joint Surg Am       Date:  1971-10       Impact factor: 5.284

5.  Spinal-cord syndrome due to non-compressive Paget's disease of bone: a spinal-artery steal phenomenon reversible with calcitonin.

Authors:  L Herzberg; E Bayliss
Journal:  Lancet       Date:  1980-07-05       Impact factor: 79.321

6.  Paget's disease in the cervical spine.

Authors:  G P Janetos
Journal:  Am J Roentgenol Radium Ther Nucl Med       Date:  1966-07

7.  Skeletal distribution and biochemical parameters of Paget's disease.

Authors:  P J Meunier; C Salson; L Mathieu; M C Chapuy; P Delmas; C Alexandre; S Charhon
Journal:  Clin Orthop Relat Res       Date:  1987-04       Impact factor: 4.176

8.  Paget's disease of the lumbar spine.

Authors:  P B Guyer; D F Shepherd
Journal:  Br J Radiol       Date:  1980-04       Impact factor: 3.039

9.  Pagetic arthritis. Pathophysiology and management.

Authors:  A Hadjipavlou; P Lander; H Srolovitz
Journal:  Clin Orthop Relat Res       Date:  1986-07       Impact factor: 4.176

Review 10.  The spine in Paget's disease.

Authors:  C Dell'Atti; V N Cassar-Pullicino; R K Lalam; B J Tins; P N M Tyrrell
Journal:  Skeletal Radiol       Date:  2007-04-05       Impact factor: 2.199

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