Literature DB >> 20177051

Characteristics, performance measures, and in-hospital outcomes of the first one million stroke and transient ischemic attack admissions in get with the guidelines-stroke.

Gregg C Fonarow1, Mathew J Reeves, Eric E Smith, Jeffrey L Saver, Xin Zhao, Dai Wai Olson, Adrian F Hernandez, Eric D Peterson, Lee H Schwamm.   

Abstract

BACKGROUND: Stroke results in substantial death and disability. To address this burden, Get With The Guideline (GWTG)-Stroke was developed to facilitate the measurement, tracking, and improvement in quality of care and outcomes for acute stroke and transient ischemic attack (TIA) patients in the United States. METHODS AND
RESULTS: We analyzed the characteristics, performance measures, and in-hospital outcomes in the first 1 000 000 acute ischemic stroke, intracerebral hemorrhage, subarachnoid hemorrhage, and TIA admissions from 1392 hospitals that participated in the GWTG-Stroke Program 2003 to 2009. Patients were 53.5% women, 73.3% white, and with mean age of 70.1+/-14.9 years. There were 601 599 (60.2%) ischemic strokes, 108 671 (10.9%) intracerebral hemorrhages, 34 945 (3.5%) subarachnoid hemorrhages, 26 977 (2.7%) strokes not classified, and 227 788 (22.8%) TIAs. Performance measures showed small to moderate differences by cerebrovascular event type. In-hospital mortality rate was highest among intracerebral hemorrhage (25.0%) and subarachnoid hemorrhage (20.4%), and intermediate in ischemic stroke (5.5%) patients and lowest among TIA patients (0.3%). Significant improvements over time from 2003 to 2009 in quality of care were observed: all-or-none measure, 44.0% versus 84.3% (+40.3%, P<0.0001). After adjustment for patient and hospital variables, the cumulative adjusted odds ratio for the all-or-none measure over the 6 years was 9.4 (95% confidence interval, 8.3 to 10.6, P<0.0001). Temporal improvements in length of stay and risk-adjusted in-hospital mortality rate (for ischemic stroke and TIA) were also observed.
CONCLUSIONS: With more than 1 million patients enrolled, GWTG-Stroke represents an integrated stroke and TIA registry that supports national surveillance, innovative research, and sustained quality improvement efforts facilitating evidence-based stroke/TIA care.

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Mesh:

Year:  2010        PMID: 20177051     DOI: 10.1161/CIRCOUTCOMES.109.921858

Source DB:  PubMed          Journal:  Circ Cardiovasc Qual Outcomes        ISSN: 1941-7713


  100 in total

1.  Predictors of increased intravenous tissue plasminogen activator use among hospitals participating in the Massachusetts Primary Stroke Service Program.

Authors:  Natalia S Rost; Eric E Smith; Muhammad A Pervez; Philip Mello; Paul Dreyer; Lee H Schwamm
Journal:  Circ Cardiovasc Qual Outcomes       Date:  2012-04-24

2.  Quality of Care for Veterans With Transient Ischemic Attack and Minor Stroke.

Authors:  Dawn M Bravata; Laura J Myers; Greg Arling; Edward J Miech; Teresa Damush; Jason J Sico; Michael S Phipps; Alan J Zillich; Zhangsheng Yu; Mathew Reeves; Linda S Williams; Jason Johanning; Seemant Chaturvedi; Fitsum Baye; Susan Ofner; Curt Austin; Jared Ferguson; Glenn D Graham; Rachel Rhude; Chad S Kessler; Donald S Higgins; Eric Cheng
Journal:  JAMA Neurol       Date:  2018-04-01       Impact factor: 18.302

3.  Comparison of Acute Ischemic Stroke Care and Outcomes Between Comprehensive Stroke Centers and Primary Stroke Centers in the United States.

Authors:  Shumei Man; Xin Zhao; Ken Uchino; M Shazam Hussain; Eric E Smith; Deepak L Bhatt; Ying Xian; Lee H Schwamm; Shreyansh Shah; Yosef Khan; Gregg C Fonarow
Journal:  Circ Cardiovasc Qual Outcomes       Date:  2018-06

4.  Stroke: Organizing the disorganized: improving TIA patient care.

Authors:  Larry B Goldstein
Journal:  Nat Rev Neurol       Date:  2011-02-22       Impact factor: 42.937

5.  Age differences in clinical characteristics, health care, and outcomes after ischemic stroke in China.

Authors:  Ya-Xian Deng; Yi-Long Wang; Bao-Qin Gao; Chun-Xue Wang; Xing-Quan Zhao; Li-Ping Liu; An-Xin Wang; Yong Zhou; Gai-Fen Liu; Wan-Liang Du; Ning Zhang; Jing Jing; Xia Meng; Jie Xu; Lin-Yu Wang; Yong-Jun Wang
Journal:  CNS Neurosci Ther       Date:  2012-08-20       Impact factor: 5.243

6.  Availability of Hospital Resources and Specialty Services for Stroke Care in North Carolina.

Authors:  Mehul D Patel; Gilson Honvoh; Antonio R Fernandez; Rhonda Cadena; Emma R Kelly; Philip McDaniel; Jane H Brice
Journal:  South Med J       Date:  2019-06       Impact factor: 0.954

Review 7.  Dual antiplatelet therapy in acute ischemic stroke.

Authors:  Negar Asdaghi; Jose G Romano
Journal:  Curr Atheroscler Rep       Date:  2015-07       Impact factor: 5.113

8.  Computed tomography findings for intracerebral hemorrhage have little incremental impact on post-stroke mortality prediction model performance.

Authors:  Darin B Zahuranec; Brisa N Sánchez; Devin L Brown; Jeffrey J Wing; Melinda A Smith; Nelda M Garcia; William J Meurer; Lewis B Morgenstern; Lynda D Lisabeth
Journal:  Cerebrovasc Dis       Date:  2012-07-14       Impact factor: 2.762

9.  Smoking and mortality in stroke survivors: can we eliminate the paradox?

Authors:  Deborah A Levine; James M Walter; Sudeep J Karve; Lesli E Skolarus; Steven R Levine; Kristine A Mulhorn
Journal:  J Stroke Cerebrovasc Dis       Date:  2014-01-15       Impact factor: 2.136

10.  Association of Intracerebral Hemorrhage Among Patients Taking Non-Vitamin K Antagonist vs Vitamin K Antagonist Oral Anticoagulants With In-Hospital Mortality.

Authors:  Taku Inohara; Ying Xian; Li Liang; Roland A Matsouaka; Jeffrey L Saver; Eric E Smith; Lee H Schwamm; Mathew J Reeves; Adrian F Hernandez; Deepak L Bhatt; Eric D Peterson; Gregg C Fonarow
Journal:  JAMA       Date:  2018-02-06       Impact factor: 56.272

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