Literature DB >> 20174678

Interaction and dynamics of the Plasmodium falciparum MTIP-MyoA complex, a key component of the invasion motor in the malaria parasite.

Jemima C Thomas1, Judith L Green, Ronald I Howson, Peter Simpson, David K Moss, Stephen R Martin, Anthony A Holder, Ernesto Cota, Edward W Tate.   

Abstract

The myosin tail domain interacting protein-myosin A (MTIP-MyoA) protein complex is an essential element of the motor driving invasion of red blood cells by the Plasmodium species that cause malaria. Here we report the key determinants of binding at the MTIP/MyoA interface, and the first structural study on the complex in solution using protein NMR.

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Year:  2010        PMID： 20174678     DOI： 10.1039/b922093c

Source DB:  PubMed          Journal:  Mol Biosyst        ISSN： 1742-2051


  14 in total

1.  Myosin B of Plasmodium falciparum (PfMyoB): in silico prediction of its three-dimensional structure and its possible interaction with MTIP.

Authors:  Paula C Hernández; Liliana Morales; Isabel C Castellanos; Moisés Wasserman; Jacqueline Chaparro-Olaya
Journal:  Parasitol Res       Date:  2017-03-07       Impact factor: 2.289

2.  Crystal structure of GAP50, the anchor of the invasion machinery in the inner membrane complex of Plasmodium falciparum.

Authors:  Jürgen Bosch; Matthew H Paige; Akhil B Vaidya; Lawrence W Bergman; Wim G J Hol
Journal:  J Struct Biol       Date:  2012-02-22       Impact factor: 2.867

3.  In vitro interaction between Plasmodium falciparum myosin B (PfMyoB) and myosin A tail interacting protein (MTIP).

Authors:  Paula C Hernández; Moisés Wasserman; Jacqueline Chaparro-Olaya
Journal:  Parasitol Res       Date:  2018-08-09       Impact factor: 2.289

4.  The compact conformation of the Plasmodium knowlesi myosin tail interacting protein MTIP in complex with the C-terminal helix of myosin A.

Authors:  Stewart Turley; Susmita Khamrui; Lawrence W Bergman; Wim G J Hol
Journal:  Mol Biochem Parasitol       Date:  2013-07-04       Impact factor: 1.759

5.  Systematic Comparison of Strategies to Achieve Soluble Expression of Plasmodium falciparum Recombinant Proteins in E. coli.

Authors:  Liliana Morales; Paula Hernández; Jacqueline Chaparro-Olaya
Journal:  Mol Biotechnol       Date:  2018-12       Impact factor: 2.695

6.  Regulation of the Plasmodium motor complex: phosphorylation of myosin A tail-interacting protein (MTIP) loosens its grip on MyoA.

Authors:  Christopher H Douse; Judith L Green; Paula S Salgado; Peter J Simpson; Jemima C Thomas; Gordon Langsley; Anthony A Holder; Edward W Tate; Ernesto Cota
Journal:  J Biol Chem       Date:  2012-08-29       Impact factor: 5.157

Review 7.  Towards a molecular understanding of the apicomplexan actin motor: on a road to novel targets for malaria remedies?

Authors:  Esa Pekka Kumpula; Inari Kursula
Journal:  Acta Crystallogr F Struct Biol Commun       Date:  2015-04-16       Impact factor: 1.056

8.  The Plasmodium Class XIV Myosin, MyoB, Has a Distinct Subcellular Location in Invasive and Motile Stages of the Malaria Parasite and an Unusual Light Chain.

Authors:  Noor A Yusuf; Judith L Green; Richard J Wall; Ellen Knuepfer; Robert W Moon; Christina Schulte-Huxel; Rebecca R Stanway; Stephen R Martin; Steven A Howell; Christopher H Douse; Ernesto Cota; Edward W Tate; Rita Tewari; Anthony A Holder
Journal:  J Biol Chem       Date:  2015-03-23       Impact factor: 5.157

9.  Targeting a dynamic protein-protein interaction: fragment screening against the malaria myosin A motor complex.

Authors:  Christopher H Douse; Nina Vrielink; Zhang Wenlin; Ernesto Cota; Edward W Tate
Journal:  ChemMedChem       Date:  2014-11-03       Impact factor: 3.466

10.  Structure-function analysis reveals that the Pseudomonas aeruginosa Tps4 two-partner secretion system is involved in CupB5 translocation.

Authors:  James A Garnett; Daniela Muhl; Christopher H Douse; Kailyn Hui; Andreas Busch; Ayodele Omisore; Yi Yang; Peter Simpson; Jan Marchant; Gabriel Waksman; Steve Matthews; Alain Filloux
Journal:  Protein Sci       Date:  2015-02-24       Impact factor: 6.725
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