Xiaoli Chen1, Renmin Ni, Yaqin Mo, Lin Li, Dongzi Yang. 1. Department of Obstetrics and Gynecology, Memorial Hospital of Sun Yat-Sen University, No.107, Yanjiang Road, Guangzhou 510120, Guangdong, China.
Abstract
BACKGROUND: This study was designed to establish appropriate body mass index (BMI) level for PCOS women and to compare metabolic abnormalities between PCOS women and control women in Southern China. METHODS: This clinical cross-sectional study included 999 PCOS patients (857 adults and 142 adolescents) and 922 age-matched controls (742 adults and 180 adolescents). RESULTS: The proportion of PCOS patients with a BMI above 23 kg/m(2) was 34.63%. Serum insulin, triglycerides, waist and waist/hip (W/H) measurements were all correlated positively with BMI in PCOS women. Prevalence of metabolic syndrome in Chinese PCOS patients was 18.9%. Receiver-operating characteristic analysis suggested that at the point of BMI > or =23 kg/m(2), the diagnostic power to detect metabolic disorders was at its best. CONCLUSIONS: PCOS patients with a BMI of 23 kg/m(2) or beyond may have a higher risk of metabolic disorders. Using an appropriate BMI level may help to improve attention to metabolic disorders among PCOS patients in Southern China.
BACKGROUND: This study was designed to establish appropriate body mass index (BMI) level for PCOSwomen and to compare metabolic abnormalities between PCOSwomen and control women in Southern China. METHODS: This clinical cross-sectional study included 999 PCOSpatients (857 adults and 142 adolescents) and 922 age-matched controls (742 adults and 180 adolescents). RESULTS: The proportion of PCOSpatients with a BMI above 23 kg/m(2) was 34.63%. Serum insulin, triglycerides, waist and waist/hip (W/H) measurements were all correlated positively with BMI in PCOSwomen. Prevalence of metabolic syndrome in Chinese PCOSpatients was 18.9%. Receiver-operating characteristic analysis suggested that at the point of BMI > or =23 kg/m(2), the diagnostic power to detect metabolic disorders was at its best. CONCLUSIONS:PCOSpatients with a BMI of 23 kg/m(2) or beyond may have a higher risk of metabolic disorders. Using an appropriate BMI level may help to improve attention to metabolic disorders among PCOSpatients in Southern China.