| Literature DB >> 20172716 |
Vincent Rerat1, Sophie Laurent, Carmen Burtéa, Benoît Driesschaert, Vincent Pourcelle, Luce Vander Elst, Robert N Muller, Jacqueline Marchand-Brynaert.
Abstract
Ultrasmall particles of iron oxide (USPIOs) coated with 3,3'-bis(phosphonate)propionic acid were covalently coupled to a home-made Arg-Gly-Asp (RGD) peptidomimetic molecule via a short oligoethylene-glycol (OEG) spacer. The conjugation rate was measured by X-ray photoelectron spectroscopy (XPS). The particle size and magnetic characteristics were kept. Our novel conjugate targeted efficiently Jurkat cells (increase of 229% vs the control). Copyright 2010 Elsevier Ltd. All rights reserved.Entities:
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Year: 2010 PMID： 20172716 DOI： 10.1016/j.bmcl.2010.01.150
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823