| Literature DB >> 20171522 |
Giovanna Gagliardi1, Louis S Constine, Vitali Moiseenko, Candace Correa, Lori J Pierce, Aaron M Allen, Lawrence B Marks.
Abstract
The literature is reviewed to identify the main clinical and dose-volume predictors for acute and late radiation-induced heart disease. A clear quantitative dose and/or volume dependence for most cardiac toxicity has not yet been shown, primarily because of the scarcity of the data. Several clinical factors, such as age, comorbidities and doxorubicin use, appear to increase the risk of injury. The existing dose-volume data is presented, as well as suggestions for future investigations to better define radiation-induced cardiac injury. Copyright 2010 Elsevier Inc. All rights reserved.Entities:
Mesh：
Year: 2010 PMID： 20171522 DOI： 10.1016/j.ijrobp.2009.04.093
Source DB: PubMed Journal: Int J Radiat Oncol Biol Phys ISSN： 0360-3016 Impact factor: 7.038