INTRODUCTION: Recurrent hemorrhagic pericardial effusion in children with no identifiable cause is a rare presentation. CASE PRESENTATION: We report the case of a 4-year-old Indian girl who presented with recurrent hemorrhagic pericardial effusion. Diffuse lymphangiomatosis was suspected when associated pulmonary involvement, soft tissue mediastinal mass, and lytic bone lesions were found. Pericardiectomy and lung biopsy confirmed the diagnosis of diffuse lymphangiohemangiomatosis. Partial clinical improvement occurred with thalidomide and low-dose radiotherapy, but our patient died from progressive respiratory failure. CONCLUSION: Diffuse lymphangiohemangiomatosis should be considered in the differential diagnosis of hemorrhagic pericardial effusion of unclear cause.
INTRODUCTION: Recurrent hemorrhagic pericardial effusion in children with no identifiable cause is a rare presentation. CASE PRESENTATION: We report the case of a 4-year-old Indian girl who presented with recurrent hemorrhagic pericardial effusion. Diffuse lymphangiomatosis was suspected when associated pulmonary involvement, soft tissue mediastinal mass, and lytic bone lesions were found. Pericardiectomy and lung biopsy confirmed the diagnosis of diffuse lymphangiohemangiomatosis. Partial clinical improvement occurred with thalidomide and low-dose radiotherapy, but our patient died from progressive respiratory failure. CONCLUSION:Diffuse lymphangiohemangiomatosis should be considered in the differential diagnosis of hemorrhagic pericardial effusion of unclear cause.
Authors: J L Faul; G J Berry; T V Colby; S J Ruoss; M B Walter; G D Rosen; T A Raffin Journal: Am J Respir Crit Care Med Date: 2000-03 Impact factor: 21.405
Authors: Jeroen Hagendoorn; Timothy P Padera; Torunn I Yock; G Petur Nielsen; Emmanuelle di Tomaso; Dan G Duda; Thomas F Delaney; Henning A Gaissert; Jennifer Pearce; Andrew E Rosenberg; Rakesh K Jain; David H Ebb Journal: Nat Clin Pract Oncol Date: 2006-12
Authors: Jeroen Hagendoorn; Torunn I Yock; Inne H M Borel Rinkes; Timothy P Padera; David H Ebb Journal: Pediatr Blood Cancer Date: 2013-11-08 Impact factor: 3.167