Literature DB >> 20169329

[Seizure and non-cardiogenic pulmonary edema after intoxication].

M Sawatzki1, O Kummer, S Krähenbühl, M Siegemund.   

Abstract

We report a case of severe intoxication with extended-release verapamil. In addition to cardiovascular toxicities with hypotension, atrioventricular block and bradycardia, the patient suffered from grand-mal seizure and pulmonary edema 13 and 48 hours respectively, after ingestion of 4.8 g of extended-release verapamil. Adverse reactions after intoxications with extended-release tablets appear delayed with prolonged manifestation of symptoms. Early and repetitive administration of activated charcoal and antegrade whole bowel lavage are crucial, even in primary asymptomatic patients.

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Year:  2010        PMID: 20169329     DOI: 10.1007/s00108-009-2544-2

Source DB:  PubMed          Journal:  Internist (Berl)        ISSN: 0020-9554            Impact factor:   0.743


  28 in total

1.  Lymphocytic intracellular calcium in a patient with complicated verapamil overdose.

Authors:  Y Ori; A Korzets; M Caneti; T Weinstein; A Chagnac; H Salman; T Malachi; U Gafter
Journal:  Am J Med Sci       Date:  2000-01       Impact factor: 2.378

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Journal:  Br J Clin Pharmacol       Date:  1995-06       Impact factor: 4.335

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Journal:  N Engl J Med       Date:  1994-03-10       Impact factor: 91.245

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Journal:  Ann Intern Med       Date:  1985-07       Impact factor: 25.391

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Journal:  Circulation       Date:  1989-09       Impact factor: 29.690

Review 7.  Pharmacology, pathophysiology and management of calcium channel blocker and beta-blocker toxicity.

Authors:  Christopher R DeWitt; Javier C Waksman
Journal:  Toxicol Rev       Date:  2004

Review 8.  Extracorporeal bypass for the treatment of verapamil poisoning.

Authors:  W G Hendren; R S Schieber; L K Garrettson
Journal:  Ann Emerg Med       Date:  1989-09       Impact factor: 5.721

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Authors:  S M Watling; J L Crain; T D Edwards; R A Stiller
Journal:  Ann Pharmacother       Date:  1992-11       Impact factor: 3.154

10.  Slow-release verapamil poisoning. Use of polyethylene glycol whole-bowel lavage and high-dose calcium.

Authors:  N Buckley; A H Dawson; D Howarth; I M Whyte
Journal:  Med J Aust       Date:  1993-02-01       Impact factor: 7.738

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