| Literature DB >> 20169329 |
M Sawatzki1, O Kummer, S Krähenbühl, M Siegemund.
Abstract
We report a case of severe intoxication with extended-release verapamil. In addition to cardiovascular toxicities with hypotension, atrioventricular block and bradycardia, the patient suffered from grand-mal seizure and pulmonary edema 13 and 48 hours respectively, after ingestion of 4.8 g of extended-release verapamil. Adverse reactions after intoxications with extended-release tablets appear delayed with prolonged manifestation of symptoms. Early and repetitive administration of activated charcoal and antegrade whole bowel lavage are crucial, even in primary asymptomatic patients.Entities:
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Year: 2010 PMID: 20169329 DOI: 10.1007/s00108-009-2544-2
Source DB: PubMed Journal: Internist (Berl) ISSN: 0020-9554 Impact factor: 0.743