ACOG Committee Opinion No. 445: antibiotics for preterm labor.

The utility of antibiotics to prolong pregnancy and reduce neonatal morbidities in women with preterm labor and intact membranes has been evaluated in numerous randomized clinical trials. Antibiotic use intended only for pregnancy prolongation in women with preterm labor with intact membranes does not have short-term neonatal benefits and may be associated with long-term harm. Thus, antibiotics should not be used for this indication in women with preterm labor and intact membranes.