Literature DB >> 20167476

Amplification of epidermal growth factor receptor gene in renal cell carcinoma.

Iman El-Hariry1, Thomas Powles, Mike R Lau, Cora N Sternberg, Alain Ravaud, Hans von der Maase, Niko Zantl, Peter Harper, Frédéric Rolland, Bruno Audhuy, Friederike Barthel, Jean-Pascal Machiels, Pina Patel, Ernst-Dietrick Kreuser, Robert E Hawkins.   

Abstract

Expression of epidermal growth factor receptor (EGFR) may be of prognostic value in renal cell cancer (RCC). Gene amplification of EGFR was investigated in a cohort of 315 patients with advanced RCC from a previously reported randomised study. Using fluorescent in situ hybridisation, only 2 patients (0.6%) had gene amplification; therefore gene amplification is of no prognostic value in RCC. Copyright 2010 Elsevier Ltd. All rights reserved.

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Year:  2010        PMID： 20167476     DOI： 10.1016/j.ejca.2010.01.011

Source DB:  PubMed          Journal:  Eur J Cancer        ISSN： 0959-8049            Impact factor:   9.162


  4 in total

Review 1.  State of the science: an update on renal cell carcinoma.

Authors:  Eric Jonasch; P Andrew Futreal; Ian J Davis; Sean T Bailey; William Y Kim; James Brugarolas; Amato J Giaccia; Ghada Kurban; Armin Pause; Judith Frydman; Amado J Zurita; Brian I Rini; Pam Sharma; Michael B Atkins; Cheryl L Walker; W Kimryn Rathmell
Journal:  Mol Cancer Res       Date:  2012-05-25       Impact factor: 5.852

2.  Sequential treatments in hereditary leiomyomatosis and renal cell carcinoma (HLRCC): Case report and review of the literature.

Authors:  Guillermo de Velasco; Cesar Munoz; Juan M Sepulveda; Daniel Castellano
Journal:  Can Urol Assoc J       Date:  2015 Mar-Apr       Impact factor: 1.862

3.  EGFR kinase-dependent and kinase-independent roles in clear cell renal cell carcinoma.

Authors:  Paolo Cossu-Rocca; Maria R Muroni; Francesca Sanges; Giovanni Sotgiu; Anna Asunis; Luciana Tanca; Daniela Onnis; Giovanna Pira; Alessandra Manca; Simone Dore; Maria G Uras; Sara Ena; Maria R De Miglio
Journal:  Am J Cancer Res       Date:  2015-12-15       Impact factor: 6.166

4.  RIN1 promotes renal cell carcinoma malignancy by activating EGFR signaling through Rab25.

Authors:  Zi-Hao Feng; Yong Fang; Liang-Yun Zhao; Jun Lu; Yong-Qian Wang; Zhen-Hua Chen; Yong Huang; Jin-Huan Wei; Yan-Ping Liang; Jun-Jie Cen; Yi-Hui Pan; Bing Liao; Wei Chen; Jun-Hang Luo
Journal:  Cancer Sci       Date:  2017-07-03       Impact factor: 6.716
  4 in total

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