Literature DB >> 20167230

Tissue distribution of tetrodotoxin in the red-spotted newt Notophthalmus viridescens.

Dietrich Mebs1, Osamu Arakawa, Mari Yotsu-Yamashita.   

Abstract

High levels of tetrodotoxin (TTX) and of its analogue 6-epi-tetrodotoxin have been detected in skin and liver extracts of the red-spotted newt Notophthalmus viridescens assayed by a post-column fluorescent-HPLC system. Using a monoclonal antibody-based immunoenzymatic technique, TTX was localized in the granular glands of the epidermis as well as in the muscle layer between the muscle fibres, but also in most organs suggesting that TTX is stored in the whole body of the newt and is secreted by skin glands. 2010 Elsevier Ltd. All rights reserved.

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Year:  2010        PMID： 20167230     DOI： 10.1016/j.toxicon.2010.02.009

Source DB:  PubMed          Journal:  Toxicon        ISSN： 0041-0101            Impact factor:   3.033


  10 in total

1.  Evolutionary history of a complex adaptation: tetrodotoxin resistance in salamanders.

Authors:  Charles T Hanifin; William F Gilly
Journal:  Evolution       Date:  2014-12-16       Impact factor: 3.694

Review 2.  Tetrodotoxin: chemistry, toxicity, source, distribution and detection.

Authors:  Vaishali Bane; Mary Lehane; Madhurima Dikshit; Alan O'Riordan; Ambrose Furey
Journal:  Toxins (Basel)       Date:  2014-02-21       Impact factor: 4.546

3.  Intracellular immunohistochemical detection of tetrodotoxin in Pleurobranchaea maculata (Gastropoda) and Stylochoplana sp. (Turbellaria).

Authors:  Lauren R Salvitti; Susanna A Wood; Leigh Winsor; Stephen Craig Cary
Journal:  Mar Drugs       Date:  2015-01-28       Impact factor: 5.118

Review 4.  Emergent toxins in North Atlantic temperate waters: a challenge for monitoring programs and legislation.

Authors:  Marisa Silva; Vijaya K Pratheepa; Luis M Botana; Vitor Vasconcelos
Journal:  Toxins (Basel)       Date:  2015-03-16       Impact factor: 4.546

5.  Tetrodotoxin poisoning caused by Goby fish consumption in southeast China: a retrospective case series analysis.

Authors:  Jie You; YaJun Yue; Feng Xing; Wei Xia; ShaoYang Lai; FengLei Zhang
Journal:  Clinics (Sao Paulo)       Date:  2015-01       Impact factor: 2.365

6.  Variations in tetrodotoxin levels in populations of Taricha granulosa are expressed in the morphology of their cutaneous glands.

Authors:  Pedro Luiz Mailho-Fontana; Carlos Jared; Marta Maria Antoniazzi; Juliana Mozer Sciani; Daniel Carvalho Pimenta; Amber N Stokes; Taran Grant; Edmund D Brodie; Edmund D Brodie
Journal:  Sci Rep       Date:  2019-12-06       Impact factor: 4.379

7.  The skin microbiome facilitates adaptive tetrodotoxin production in poisonous newts.

Authors:  Patric M Vaelli; Kevin R Theis; Janet E Williams; Lauren A O'Connell; James A Foster; Heather L Eisthen
Journal:  Elife       Date:  2020-04-07       Impact factor: 8.140

Review 8.  An Overview of the Anatomical Distribution of Tetrodotoxin in Animals.

Authors:  Daria I Melnikova; Timur Yu Magarlamov
Journal:  Toxins (Basel)       Date:  2022-08-22       Impact factor: 5.075

9.  Novel Polyclonal Antibody Raised against Tetrodotoxin Using Its Haptenic Antigen Prepared from 4,9-anhydrotetrodotoxin Reacted with 1,2-Ethaneditiol and Further Reacted with Keyhole Limpet Hemocyanin.

Authors:  Shigeru Sato; Suzuka Takaishi; Ko Yasumoto; Shugo Watabe
Journal:  Toxins (Basel)       Date:  2019-09-20       Impact factor: 4.546

10.  Tetrodotoxins Secretion and Voltage-Gated Sodium Channel Adaptation in the Ribbon Worm Kulikovia alborostrata (Takakura, 1898) (Nemertea).

Authors:  Anna E Vlasenko; Vasiliy G Kuznetsov; Grigorii V Malykin; Alexandra O Pereverzeva; Peter V Velansky; Konstantin V Yakovlev; Timur Yu Magarlamov
Journal:  Toxins (Basel)       Date:  2021-08-29       Impact factor: 4.546
  10 in total

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