Literature DB >> 20164850

Nucleoside analog ARC targets Mcl-1 to induce apoptosis in leukemia cells.

U G Bhat, A L Gartel.   

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Year:  2010        PMID: 20164850      PMCID: PMC3201742          DOI: 10.1038/leu.2010.3

Source DB:  PubMed          Journal:  Leukemia        ISSN: 0887-6924            Impact factor:   11.528


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  8 in total

1.  Mcl-1 down-regulation potentiates ABT-737 lethality by cooperatively inducing Bak activation and Bax translocation.

Authors:  Shuang Chen; Yun Dai; Hisashi Harada; Paul Dent; Steven Grant
Journal:  Cancer Res       Date:  2007-01-15       Impact factor: 12.701

2.  An inhibitor of Bcl-2 family proteins induces regression of solid tumours.

Authors:  Tilman Oltersdorf; Steven W Elmore; Alexander R Shoemaker; Robert C Armstrong; David J Augeri; Barbara A Belli; Milan Bruncko; Thomas L Deckwerth; Jurgen Dinges; Philip J Hajduk; Mary K Joseph; Shinichi Kitada; Stanley J Korsmeyer; Aaron R Kunzer; Anthony Letai; Chi Li; Michael J Mitten; David G Nettesheim; ShiChung Ng; Paul M Nimmer; Jacqueline M O'Connor; Anatol Oleksijew; Andrew M Petros; John C Reed; Wang Shen; Stephen K Tahir; Craig B Thompson; Kevin J Tomaselli; Baole Wang; Michael D Wendt; Haichao Zhang; Stephen W Fesik; Saul H Rosenberg
Journal:  Nature       Date:  2005-05-15       Impact factor: 49.962

3.  Differential sensitivity of human colon cancer cell lines to the nucleoside analogs ARC and DRB.

Authors:  Uppoor G Bhat; Andrei L Gartel
Journal:  Int J Cancer       Date:  2008-03-15       Impact factor: 7.396

4.  Novel anticancer compounds induce apoptosis in melanoma cells.

Authors:  Uppoor G Bhat; Patricia A Zipfel; Douglas S Tyler; Andrei L Gartel
Journal:  Cell Cycle       Date:  2008-06-30       Impact factor: 4.534

5.  Transcriptional and translational control of Mcl-1 during apoptosis.

Authors:  Daniel Iglesias-Serret; Maria Piqué; Joan Gil; Gabriel Pons; José M López
Journal:  Arch Biochem Biophys       Date:  2003-09-15       Impact factor: 4.013

6.  A novel transcriptional inhibitor induces apoptosis in tumor cells and exhibits antiangiogenic activity.

Authors:  Senthil K Radhakrishnan; Andrei L Gartel
Journal:  Cancer Res       Date:  2006-03-15       Impact factor: 12.701

7.  Proapoptotic compound ARC targets Akt and N-myc in neuroblastoma cells.

Authors:  S K Radhakrishnan; M Halasi; U G Bhat; R T Kurmasheva; P J Houghton; A L Gartel
Journal:  Oncogene       Date:  2007-09-03       Impact factor: 9.867

8.  ARC (NSC 188491) has identical activity to Sangivamycin (NSC 65346) including inhibition of both P-TEFb and PKC.

Authors:  Luke H Stockwin; Sherry X Yu; Howard Stotler; Melinda G Hollingshead; Dianne L Newton
Journal:  BMC Cancer       Date:  2009-02-20       Impact factor: 4.430

  8 in total
  5 in total

1.  ARC synergizes with ABT-737 to induce apoptosis in human cancer cells.

Authors:  Uppoor G Bhat; Bulbul Pandit; Andrei L Gartel
Journal:  Mol Cancer Ther       Date:  2010-06-01       Impact factor: 6.261

Review 2.  Advances in the development of nucleoside and nucleotide analogues for cancer and viral diseases.

Authors:  Lars Petter Jordheim; David Durantel; Fabien Zoulim; Charles Dumontet
Journal:  Nat Rev Drug Discov       Date:  2013-06       Impact factor: 84.694

3.  Understanding sensitivity to BH3 mimetics: ABT-737 as a case study to foresee the complexities of personalized medicine.

Authors:  Vasileios A Stamelos; Charles W Redman; Alan Richardson
Journal:  J Mol Signal       Date:  2012-08-16

4.  Transcription inhibition as a therapeutic target for cancer.

Authors:  Christine M Stellrecht; Lisa S Chen
Journal:  Cancers (Basel)       Date:  2011-11-23       Impact factor: 6.639

5.  Circumvention of Mcl-1-dependent drug resistance by simultaneous Chk1 and MEK1/2 inhibition in human multiple myeloma cells.

Authors:  Xin-Yan Pei; Yun Dai; Jessica Felthousen; Shuang Chen; Yukie Takabatake; Liang Zhou; Leena E Youssefian; Michael W Sanderson; Wesley W Bodie; Lora B Kramer; Robert Z Orlowski; Steven Grant
Journal:  PLoS One       Date:  2014-03-04       Impact factor: 3.240

  5 in total

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